Environmental influences on the fetus and neonate—timing, mechanisms of action and effects on subsequent adult function

Rhind, S.M.; Rae, M.T.; Brooks, A.N.

Abstract

Environmental influences on fetal and neonatal development can affect neural, reproductive, immune and cardiovascular function in adult humans and animals. The effects can be exerted at many different stages of development from before conception to after birth. Effects may even be exerted during a preceding generation. Some known and some possible mechanisms are reviewed. Systems likely to be affected include the brain, hypothalamus, pituitary and adrenal glands and the gonads. The effects may be exerted through altered gene expression at any stage of development or through changes in organ structure or physiology.

Citation

Rhind, S., Rae, M., & Brooks, A. (2003). Environmental influences on the fetus and neonate—timing, mechanisms of action and effects on subsequent adult function. Domestic Animal Endocrinology, 25(1), 3-11. https://doi.org/10.1016/S0739-7240%2803%2900041-9

• Journal Article Type: Article
• Online Publication Date: May 27, 2003
• Publication Date: 2003-07
• Deposit Date: Jul 27, 2016
• Journal: Domestic Animal Endocrinology
• Print ISSN: 0739-7240
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 25
• Issue: 1
• Pages: 3-11
• DOI: https://doi.org/10.1016/S0739-7240%2803%2900041-9
• Keywords: Fetus; Fetal programming; Development; Hormones
• Public URL: http://researchrepository.napier.ac.uk/Output/317812
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0739724003000419
• Additional Information: Reproductive Physiology: Proceedings of a workshop held at the Institute for Animal Science Mariensee, Germany