Outputs (20)

Student engagement and curriculum design within Clinical Exercise Physiology (2023)
Presentation / Conference Contribution
Leggate, M., Pitkethly, A., & De Klerk, T. (2023, April). Student engagement and curriculum design within Clinical Exercise Physiology. Paper presented at Innovation and Updates in Teaching and Student Education across Physiology and STEM in the UK, Leeds, UK

This project aims to determine the perceptions of both graduate and current students studying on a MSc programme in Clinical Exercise Science. This project aims to redevelop our current provision to align with the new Clinical Exercise Physiology Fra... Read More about Student engagement and curriculum design within Clinical Exercise Physiology.

Addressing concerns between curricula and employability: Can we do more? (2022)
Presentation / Conference Contribution
Leggate, M., & Pitkethly, A. (2022, June). Addressing concerns between curricula and employability: Can we do more?. Paper presented at Advance HE's Curriculum Symposium, Leeds

Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age (2021)
Journal Article
Lithgow, H., Florida‐James, G., Ross, M., Duncan, G., & Leggate, M. (2021). Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age. Experimental Physiology, 106(7), 1460-1469. https://doi.org/10.1113/ep089480

Vitamin D plays a key role in the modulation of the immune system, mediated through the intracellular vitamin D receptor (VDR). Exercise has been shown to influence the activity and availability of the VDR. This study aimed to investigate the effect... Read More about Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age.

The effects of age and acute aerobic and resistance exercise on circulating T lymphocyte vitamin D receptor (VDR) expression in healthy males (2019)
Presentation / Conference Contribution
Leggate, M., Florida-James, G., Ross, M., Jurevicius, M., Duncan, G., & Lithgow, H. (2019, December). The effects of age and acute aerobic and resistance exercise on circulating T lymphocyte vitamin D receptor (VDR) expression in healthy males. Presented at Future Physiology, Liverpool, UK

A low vitamin D status has been identified as an association risk factor in the etiology of numerous chronic diseases, with older adults identified as generally more deficient than younger populations. Exercise has been shown to act as a direct and i... Read More about The effects of age and acute aerobic and resistance exercise on circulating T lymphocyte vitamin D receptor (VDR) expression in healthy males.

Exercise Window Trial in Newly Diagnosed Breast Cancer–Letter (2019)
Journal Article
Sims, A. H., Leggate, M., & Campbell, A. (2019). Exercise Window Trial in Newly Diagnosed Breast Cancer–Letter. Clinical Cancer Research, 25(24), 7609-7610. https://doi.org/10.1158/1078-0432.ccr-19-2571

The effect of acute exercise on T cell vitamin D receptor (VDR) expression in young and older males (2018)
Presentation / Conference Contribution
Leggate, M., Lithgow, H., Florida-James, G., & Barlow, P. (2018, July). The effect of acute exercise on T cell vitamin D receptor (VDR) expression in young and older males. Presented at 23rd Annual Congress of the European College of Sport Science (ECSS), Dublin, Ireland

A low vitamin D status has been identified as an association risk factor in the etiology of numerous chronic diseases, with older adults identified as generally more deficient than younger populations. Exercise has been shown to act as a direct and i... Read More about The effect of acute exercise on T cell vitamin D receptor (VDR) expression in young and older males.

The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults (2018)
Journal Article
Lithgow, H. M., Florida-James, G., & Leggate, M. (2018). The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults. Physiological Reports, 6(9), Article e13684. https://doi.org/10.14814/phy2.13684

High intensity intermittent training (HIIT) has been shown to reduce the risk of chronic conditions including the development of type 2 diabetes mellitus (T2DM). Independently, a low vitamin D status has also been linked to the prevalence of T2DM. Th... Read More about The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults.

The Effect of a Single Bout of High Intensity Intermittent Exercise on Glucose Tolerance in Non-diabetic Older Adults (2018)
Journal Article
Lithgow, H., & Leggate, M. (2018). The Effect of a Single Bout of High Intensity Intermittent Exercise on Glucose Tolerance in Non-diabetic Older Adults. International Journal of Exercise Science, 11(3), 95-105

Our aim was to investigate the acute effects of a single bout of high intensity intermittent training (HIIT) on glucose tolerance and other physiological and metabolic markers in non-diabetic older adults. Fourteen healthy older adults (age, 64 ± 2 y... Read More about The Effect of a Single Bout of High Intensity Intermittent Exercise on Glucose Tolerance in Non-diabetic Older Adults.

The combined effect of high‐intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults (2017)
Presentation / Conference Contribution
Leggate, M., Lithgow, H., & Florida-James, G. (2017, May). The combined effect of high‐intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults. Poster presented at Cell Symposia: Exercise Metabolism, Gothenburg, Sweden

The aim of this study was to investigate if there was a synergistic effect of high intensity intermittent training (HIIT) and vitamin D3 supplementation on glycaemic control. Twenty participants (age, 34±9y; BMI, 31.4±2.8 kg·m-2) completed 6 weeks HI... Read More about The combined effect of high‐intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults.

Subclinical diastolic dysfunction in young adults with Type 2 diabetes mellitus: a multiparametric contrast-enhanced cardiovascular magnetic resonance pilot study assessing potential mechanisms (2014)
Journal Article
Khan, J. N., Wilmot, E. G., Leggate, M., Singh, A., Yates, T., Nimmo, M., …McCann, G. P. (2014). Subclinical diastolic dysfunction in young adults with Type 2 diabetes mellitus: a multiparametric contrast-enhanced cardiovascular magnetic resonance pilot study assessing potential mechanisms. European heart journal cardiovascular Imaging, 15(11), 1263-1269. https://doi.org/10.1093/ehjci/jeu121

Aims To assess the cardiac, vascular, anthropometric, and biochemical determinants of subclinical diastolic dysfunction in younger adults with Type 2 diabetes mellitus (T2DM) using multiparametric contrast-enhanced cardiovascular magnetic resonance... Read More about Subclinical diastolic dysfunction in young adults with Type 2 diabetes mellitus: a multiparametric contrast-enhanced cardiovascular magnetic resonance pilot study assessing potential mechanisms.