The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults

Lithgow, Hannah Margaret; Florida-James, Geraint; Leggate, Melanie

Abstract

High intensity intermittent training (HIIT) has been shown to reduce the risk of chronic conditions including the development of type 2 diabetes mellitus (T2DM). Independently, a low vitamin D status has also been linked to the prevalence of T2DM. The aim of this study was to investigate if there was a synergistic metabolic effect of HIIT and vitamin D supplementation on glycaemic control. Twenty male and female participants (age, 34 ± 9 y; BMI, 31.4 ± 2.8 kg·m-2) completed 6 weeks HIIT, and were randomised to ingest 100 µg/day of vitamin D3 or placebo. Response to an oral glucose tolerance test (OGTT) was determined at baseline and 72 h post-intervention. Glucose tolerance was improved as a result of the HIIT intervention, shown through a reduction in glucose and insulin concentrations during the OGTT, accompanied with a decrease in glucose (829 ± 110 to 786 ± 139 mmol·h-1·L-1; P=0.043) and insulin (8101 ± 4755 to 7024 ± 4489 mU·h-1·L-1; P=0.049) area under the curve (AUC). Supplementation increased 25-hydroxyvitamin D3 concentration by 120 % to a sufficiency status (P

Citation

Lithgow, H. M., Florida-James, G., & Leggate, M. (2018). The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults. Physiological Reports, 6(9), Article e13684. https://doi.org/10.14814/phy2.13684

• Journal Article Type: Article
• Acceptance Date: Mar 15, 2018
• Online Publication Date: Apr 30, 2018
• Publication Date: 2018-05
• Deposit Date: Apr 5, 2018
• Publicly Available Date: Apr 6, 2018
• Journal: Physiological Reports
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 6
• Issue: 9
• Article Number: e13684
• DOI: https://doi.org/10.14814/phy2.13684
• Keywords: Vitamin D, Glucose tolerance, High intensity intermittent training,
• Public URL: http://researchrepository.napier.ac.uk/Output/1145158
• Contract Date: Apr 5, 2018