Enhancing the stability and the delivery of lactoferrin for prevention and/or treatment of covid-19 respiratory disease. Feb 14, 2022 - Nov 13, 2023
Lactoferrin (LF) is a glycoprotein which is widely contained in many secretory fluids, mainly milk but also saliva, tears, and nasal secretions. Many scientific reports supported an application of this glycoprotein in the prophylaxis and treatment of...
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Projects (12)
Developing an adoptive regulatory T cell therapy for the treatment of rheumatoid arthritis Mar 1, 2021 - Feb 28, 2024
The immune system contains a balance of cells that turn responses ‘on’ and those that turn it ‘off’. When this balance breaks down, inappropriate immune responses can attack healthy tissues causing autoimmune disease, such as rheuma...
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Development of an in vitro suppression assay to assess functionality of therapeutic regulatory T cell for the treatment of rheumatoid arthritis Jun 11, 2023 - Aug 14, 2024
MRS Summer Studentship for ENU Undergrad student Martin Swapp - 8 weeks in duration over summer 2023
False webs: Network to address the misinformation pandemic Sep 1, 2023 - Aug 31, 2025
Fake news (inaccurate information) peaked during the pandemic with around 46 000 daily Twitter posts containing false information (Lupi, 2020). In Europe over 70% people regularly encounter fake news (UNESCO, 2021). The Scottish government has recent...
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Medical Research Scotland Vacation Scholarship Jun 13, 2022 - Aug 8, 2023
Investigating the anti-metastatic potential of Honokiol by attenuating KISS1/ KISS1R signaling
Exploiting micofluidic devices for physiologically relavent drug screening against human pathogens Jun 1, 2022 - Jul 27, 2022
Undergraduate student summer project (8 weeks)
TB/COVID-19 co-infections within a 3D in vitro imaging system Apr 1, 2021 - Mar 31, 2022
TB/COVID-19 co-infections within a 3D in vitro imaging system
Does Residual Beta Cell Function and Exercise Offer Synergistic Protection Against Hyperglycaemic Induced Circulating Vasoprotective Dysfunction in Type 1 Diabetes? Sep 1, 2021 - Aug 31, 2022
For people with T1D, exercise is beneficial, potentially reducing the progression of diabetes-related complications. Many people (up to 80%) with T1D still release small amounts of insulin together with C-peptide, a molecule involved in the creation...
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Host Defence Peptides as novel modulators of autophagy in Inflammatory Bowel Disease Oct 1, 2019 - Dec 31, 2022
Increasing numbers of patients are diagnosed with inflammatory bowel disease (IBD) each year, both in the United Kingdom and worldwide. Most drugs in current use for the treatment of IBD target the immune system to reduce inflammation and induce remi...
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Cathelicidins as Novel Therapeutic Antivirals for Dengue Infection Apr 1, 2019 - Mar 31, 2022
A significant challenge faced by modern society is the lack of therapeutics for a large number of infections, particularly those that are endemic or widely spread in developing countries. Dengue is one such infection which is endemic inIndonesia - it...
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IBD drug effect on autophagy (IDEA) Oct 1, 2017 - Mar 31, 2018
An investigation of commonly used IBD drugs on autophagy pathway activity and potential therapeutic benefit for treatment of paediatric IBD
An investigation of commonly used IBD drugs on autophagy pathway activity and potential therapeutic benefit for the treatment of paediatric IBD Sep 1, 2014 - Aug 31, 2017
Recent genetic discoveries, principally identification of NOD2 and ATG16L1 as susceptibility loci, strongly implicate a dysregulated host response to enteric bacteria and the autophagy pathway in the pathogenesis of Crohn’s disease (CD). Several micr...
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