Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials
(2020)
Journal Article
Pazan, F., Petrovic, M., Cherubini, A., Onder, G., Cruz-Jentoft, A. J., Denkinger, M., van der Cammen, T. J. M., Stevenson, J. M., Ibrahim, K., Rajkumar, C., Bakken, M. S., Baeyens, J.-P., Crome, P., Frühwald, T., Gallaghar, P., Guðmundsson, A., Knol, W., O’Mahony, D., Pilotto, A., Rönnemaa, E., …Wehling, M. (2021). Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials. European Journal of Clinical Pharmacology, 77(1), 1-12. https://doi.org/10.1007/s00228-020-02951-8
Background
Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest frailty.
Methods
A literatur...
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