All Outputs (4)

Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status (2012)
Journal Article
Prach, M., Stone, V., & Proudfoot, L. (2012). Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status. Toxicology and Applied Pharmacology, 266(1), 19-26. https://doi.org/10.1016/j.taap.2012.10.020

Zinc oxide (ZnO) particle induced cytotoxicity was dependent on size, charge and solubility, factors which at sublethal concentrations may influence the activation of the human monocytic cell line THP1. ZnO nanoparticles (NP; average diameter 70 nm)... Read More about Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status.

Role of EGFR in intestinal barrier function in response to challenges with silver nanoparticles and enteric pathogens (2012)
Presentation / Conference Contribution
Sehgal, A., Hutchison, G., Proudfoot, L., Malone, E., Cameron, P., & Fraser-Pitt, D. (2012, July). Role of EGFR in intestinal barrier function in response to challenges with silver nanoparticles and enteric pathogens. Poster presented at Society for Appli

Caenorhabditis elegans as a Model for the Assessment of Nanomaterial Toxicity (2012)
Presentation / Conference Contribution
Nicol, L., Malone, E., & Proudfoot, L. (2012, April). Caenorhabditis elegans as a Model for the Assessment of Nanomaterial Toxicity. Poster presented at British Society for Parasitology Conference, 50th Anniversary, Glasgow

Nanomaterials, having at least one dimension less than 100nm, have unique physico-chemical properties due to their small size, large surface area and surface reactivity. Manufactured nanomaterials have enormous potential in industrial, pharmaceutical... Read More about Caenorhabditis elegans as a Model for the Assessment of Nanomaterial Toxicity.

Nanoparticles and Neutrophil Activation (2012)
Presentation / Conference Contribution
Dickson, C., Prach, M., Fraser, J., Ingram, L., Barlow, P., Hutchison, G., …Malone, E. (2012, February). Nanoparticles and Neutrophil Activation. Presented at NanoImpactNet-QNANO conference - European Network on the Health and Environmental Impact of Na

Neutrophils, the rapid responders of the innate immune system, are central to the initial immune responses of a host to foreign particles. Circulating in the blood, they are the predominant leukocyte (40-75%), and are positioned to rapidly migrate to... Read More about Nanoparticles and Neutrophil Activation.