Choice of spectroscopic line shape model affects metabolite peak areas and area ratios.
(2000)
Journal Article
Marshall, I., Bruce, S. D., Higinbotham, J., MacLullich, A., Wardlaw, J. M., Ferguson, K. J., & Seckl, J. (2000). Choice of spectroscopic line shape model affects metabolite peak areas and area ratios. Magnetic Resonance in Medicine, 44, 646-649. doi:10.1002/1522-2594(200010)44:43.0.CO;2-0
The use of Lorentzian model lineshapes leads to systematic errors in the quantification of in vivo (1)H NMR spectra. Experimental lineshapes are better modeled by the Voigt (mixed Lorentzian-Gaussian) function, leading to more accurate fits (reduced... Read More about Choice of spectroscopic line shape model affects metabolite peak areas and area ratios..