Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents
(2018)
Journal Article
Ammar, U. M., Abdel-Maksoud, M. S., & Oh, C. (2018). Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents. European Journal of Medicinal Chemistry, 158, 144-166. https://doi.org/10.1016/j.ejmech.2018.09.005
Frequent oncogenic mutations have been identified in MAPK (mitogen-activated protein kinase) signaling pathway components. As a result, MAPK pathway is associated with human cancer initiation, in particular RAF (rapidly accelerated fibrosarcoma) comp... Read More about Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents.