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Effects of prenatal undernutrition on emotional reactivity and cognitive flexibility in adult sheep (2003)
Journal Article
Erhard, H. W., Boissy, A., Rae, M. T., & Rhind, S. M. (2004). Effects of prenatal undernutrition on emotional reactivity and cognitive flexibility in adult sheep. Behavioural Brain Research, 151(1-2), 25-35. https://doi.org/10.1016/j.bbr.2003.08.003

The experiment reported was designed to test two hypotheses: that prenatal undernutrition (a) increases emotional reactivity and (b) impairs cognitive flexibility in sheep. The mothers of one group were fed live weight maintenance requirements throug... Read More about Effects of prenatal undernutrition on emotional reactivity and cognitive flexibility in adult sheep.

Glucocorticoid metabolism and reproduction: a tale of two enzymes (2003)
Journal Article
Michael, A., Thurston, L., & Rae, M. (2003). Glucocorticoid metabolism and reproduction: a tale of two enzymes. Reproduction, 126, 425-441. https://doi.org/10.1530/rep.0.1260425

Within potential target cells, the actions of physiological glucocorticoids (cortisol and corticosterone) are modulated by isoforms of the enzyme 11 beta-hydroxysteroid dehydrogenase (11 beta HSD). To date, two isoforms of 11 beta HSD have been clone... Read More about Glucocorticoid metabolism and reproduction: a tale of two enzymes.

Environmental influences on the fetus and neonate—timing, mechanisms of action and effects on subsequent adult function (2003)
Journal Article
Rhind, S., Rae, M., & Brooks, A. (2003). Environmental influences on the fetus and neonate—timing, mechanisms of action and effects on subsequent adult function. Domestic Animal Endocrinology, 25(1), 3-11. https://doi.org/10.1016/S0739-7240%2803%2900041

Environmental influences on fetal and neonatal development can affect neural, reproductive, immune and cardiovascular function in adult humans and animals. The effects can be exerted at many different stages of development from before conception to a... Read More about Environmental influences on the fetus and neonate—timing, mechanisms of action and effects on subsequent adult function.

Undernutrition of ewe lambs in utero and in early post-natal life does not affect hypothalamic–pituitary function in adulthood (2003)
Journal Article
Borwick, S., Rae, M., Brooks, J., McNeilly, A., Racey, P., & Rhind, S. (2003). Undernutrition of ewe lambs in utero and in early post-natal life does not affect hypothalamic–pituitary function in adulthood. Animal Reproduction Science, 77(1-2), 61-70. h

The effect of undernutrition in utero, during late gestation (from day 100), and early neonatal life on hypothalamic–pituitary function was investigated in female lambs born to ewes fed rations calculated to provide either 100% (high; H) or 70% (low;... Read More about Undernutrition of ewe lambs in utero and in early post-natal life does not affect hypothalamic–pituitary function in adulthood.

Lysyl Oxidase Gene Expression and Enzyme Activity in the Rat Ovary: Regulation by Follicle-Stimulating Hormone, Androgen, and Transforming Growth Factor-β Superfamily Members in Vitro (2003)
Journal Article
Harlow, C. R., Rae, M., Davidson, L., Trackman, P. C., & Hillier, S. G. (2003). Lysyl Oxidase Gene Expression and Enzyme Activity in the Rat Ovary: Regulation by Follicle-Stimulating Hormone, Androgen, and Transforming Growth Factor-β Superfamily Members

Lysyl oxidase (LOX) catalyzes the final enzymatic reaction required for cross-linking of collagen and elastin fibers and therefore has a crucial role in regulating the formation and maintenance of extracellular matrix in the ovary. LOX mRNA is abunda... Read More about Lysyl Oxidase Gene Expression and Enzyme Activity in the Rat Ovary: Regulation by Follicle-Stimulating Hormone, Androgen, and Transforming Growth Factor-β Superfamily Members in Vitro.