All Outputs (3)

Anti-inflammatory steroid signalling in the human peritoneum (2008)
Journal Article
Fegan, K. S., Rae, M. T., Critchley, H. O. D., & Hillier, S. G. (2008). Anti-inflammatory steroid signalling in the human peritoneum. Journal of Endocrinology, 196, 369-376. https://doi.org/10.1677/JOE-07-0419

Peritoneal surface epithelial (PSE) cells participate in adhesion formation following inflammatory injury yet adjacent ovarian SE (OSE) cells regenerate without scarification after ovulation. OSE cells show inflammation-associated expression of 11β h... Read More about Anti-inflammatory steroid signalling in the human peritoneum.

Ovulation and Ovarian Cancer (2008)
Book Chapter
Hillier, S. G., Rae, M. T., & Gubbay, O. (2008). Ovulation and Ovarian Cancer. In Hormonal Carcinogenesis V; (171-178). Springer. https://doi.org/10.1007/978-0-387-69080-3_16

Ovarian cancer (OC) most frequently arises from the ovarian surface epithelium (OSE), which comprises a single layer of mesothelial, squamous-to-cuboidal cells covering the entire surface of the ovary (1). This dynamic cellular layer and underlying b... Read More about Ovulation and Ovarian Cancer.

Glucocorticoid receptor-mediated regulation of MMP9 gene expression in human ovarian surface epithelial cells (2008)
Journal Article
Rae, M. T., Price, D., Harlow, C. R., Critchley, H. O. D., & Hillier, S. G. (2009). Glucocorticoid receptor-mediated regulation of MMP9 gene expression in human ovarian surface epithelial cells. Fertility and Sterility, 92(2), 703-708. https://doi.org/10.1016/j.fertnstert.2008.06.040

Objective
To obtain proof-of-concept that locally produced anti-inflammatory steroids suppress ovulation-associated extracellular matrix proteases in human ovarian surface epithelial (OSE) cells.

Design
Primary OSE cell cultures treated with int... Read More about Glucocorticoid receptor-mediated regulation of MMP9 gene expression in human ovarian surface epithelial cells.