All Outputs (7)

An X-linked meiotic drive allele has strong, recessive fitness costs in female Drosophila pseudoobscura (2019)
Journal Article
Larner, W., Price, T., Holman, L., & Wedell, N. (2019). An X-linked meiotic drive allele has strong, recessive fitness costs in female Drosophila pseudoobscura. Proceedings of the Royal Society B: Biological Sciences, 286(1916), https://doi.org/10.1098/rs

Selfish ‘meiotic drive’ alleles are transmitted to more than 50% of offspring, allowing them to rapidly invade populations even if they reduce the fitness of individuals carrying them. Theory predicts that drivers should either fix or go extinct, yet... Read More about An X-linked meiotic drive allele has strong, recessive fitness costs in female Drosophila pseudoobscura.

Mother’s curse and indirect genetic effects: Do males matter to mitochondrial genome evolution? (2019)
Journal Article
Keaney, T. A., Wong, H. W. S., Dowling, D. K., Jones, T. M., & Holman, L. (2020). Mother’s curse and indirect genetic effects: Do males matter to mitochondrial genome evolution?. Journal of Evolutionary Biology, 33(2), 189-201. https://doi.org/10.1111/j

Maternal inheritance of mitochondrial DNA (mtDNA) was originally thought to prevent any response to selection on male phenotypic variation attributable to mtDNA, resulting in a male‐biased mtDNA mutation load (“mother's curse”). However, the theory u... Read More about Mother’s curse and indirect genetic effects: Do males matter to mitochondrial genome evolution?.

Fitness consequences of the selfish supergene Segregation Distorter (2019)
Journal Article
Wong, H. W. S., & Holman, L. (2020). Fitness consequences of the selfish supergene Segregation Distorter. Journal of Evolutionary Biology, 33(1), 89-100. https://doi.org/10.1111/jeb.13549

Segregation distorters are selfish genetic elements that subvert Mendelian inheritance, often by destroying gametes that do not carry the distorter. Simple theoretical models predict that distorter alleles will either spread to fixation or stabilize... Read More about Fitness consequences of the selfish supergene Segregation Distorter.

Evolutionary simulations of Z-linked suppression gene drives (2019)
Journal Article
Holman, L. (2019). Evolutionary simulations of Z-linked suppression gene drives. Proceedings of the Royal Society B: Biological Sciences, 286(1912), https://doi.org/10.1098/rspb.2019.1070

Synthetic gene drives may soon be used to suppress or eliminate populations of disease vectors, pathogens, invasive species, and agricultural pests. Recent proposals have focused on using Z-linked gene drives to control species with ZW sex determinat... Read More about Evolutionary simulations of Z-linked suppression gene drives.

Meta-analytic evidence that sexual selection improves population fitness (2019)
Journal Article
Cally, J. G., Stuart-Fox, D., & Holman, L. (2019). Meta-analytic evidence that sexual selection improves population fitness. Nature Communications, 10, Article 2017 (2019). https://doi.org/10.1038/s41467-019-10074-7

Sexual selection has manifold ecological and evolutionary consequences, making its net effect on population fitness difficult to predict. A powerful empirical test is to experimentally manipulate sexual selection and then determine how population fit... Read More about Meta-analytic evidence that sexual selection improves population fitness.

Researchers collaborate with same-gendered colleagues more often than expected across the life sciences (2019)
Journal Article
Holman, L., & Morandin, C. (2019). Researchers collaborate with same-gendered colleagues more often than expected across the life sciences. PLOS ONE, 14(4), Article e0216128. https://doi.org/10.1371/journal.pone.0216128

Evidence suggests that women in academia are hindered by conscious and unconscious biases, and often feel excluded from formal and informal opportunities for research collaboration. In addition to ensuring fairness and helping to redress gender imbal... Read More about Researchers collaborate with same-gendered colleagues more often than expected across the life sciences.

Comparative transcriptomics of social insect queen pheromones (2019)
Journal Article
Holman, L., Helanterä, H., Trontti, K., & Mikheyev, A. S. (2019). Comparative transcriptomics of social insect queen pheromones. Nature Communications, 10, Article 1593 (2019). https://doi.org/10.1038/s41467-019-09567-2

Queen pheromones are chemical signals that mediate reproductive division of labor in eusocial animals. Remarkably, queen pheromones are composed of identical or chemically similar compounds in some ants, wasps and bees, even though these taxa diverge... Read More about Comparative transcriptomics of social insect queen pheromones.