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All Outputs (8)

From ∆log kw IAM to multidimensional biomimetic chromatography: a journey to shed light on the absorption potential of therapeutics. What will the future bring? (2023)
Presentation / Conference Contribution
Russo, G. (2023, September). From ∆log kw IAM to multidimensional biomimetic chromatography: a journey to shed light on the absorption potential of therapeutics. What will the future bring?. Presented at 10th IAPC Meeting, Belgrade, Serbia

Biomimetic chromatography encompasses a range of analytical approaches aimed at mimicking the asset of biological membranes including – but not limited to – micellar liquid chromatography (MLC), immobilized artificial membranes (IAM) and immobilize... Read More about From ∆log kw IAM to multidimensional biomimetic chromatography: a journey to shed light on the absorption potential of therapeutics. What will the future bring?.

The effectiveness of biomimetic chromatography based methods in predictions of human pulmonary drug absorption (2023)
Presentation / Conference Contribution
Dillon, A., Orzek, D., MacCallum, J., & Russo, G. (2023, June). The effectiveness of biomimetic chromatography based methods in predictions of human pulmonary drug absorption. Poster presented at HPLC 2023

Nowadays immobilized artificial membranes (IAM) are commonly used for modelling drug
transport through biological lipid layers. In most published studies a compound’s lipophilicity
measurements are performed in isocratic conditions where a low pe... Read More about The effectiveness of biomimetic chromatography based methods in predictions of human pulmonary drug absorption.

De Novo Structural Elucidation Principle via In Silico Chromatographic Retention Index Prediction for Micropollutants in Wastewater (2022)
Presentation / Conference Contribution
Kajtazi, G., Wicht, K., Russo, G., Eghbali, H., & Lynen, F. (2022, May). De Novo Structural Elucidation Principle via In Silico Chromatographic Retention Index Prediction for Micropollutants in Wastewater. Poster presented at 17th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Ghent, Belgium

Micropollutants, such as pharmaceuticals, industrial chemicals, steroid hormones, etc. are defined as anthropogenic chemicals and can be found in water. It is seen as a serious threat, not just to aquatic life but also to humans, which requires the a... Read More about De Novo Structural Elucidation Principle via In Silico Chromatographic Retention Index Prediction for Micropollutants in Wastewater.

Fused deposition modeling based 3D-printing of solid phase cartridges: development and implementation (2022)
Presentation / Conference Contribution
Lynen, F., Russo, G., & Gallikova, J. (2022, May). Fused deposition modeling based 3D-printing of solid phase cartridges: development and implementation. Paper presented at 17th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Ghent, Belgium

In this work fused deposition modeling (FDM) based 3D-printing is used for the manufacturing of cartridges for solid phase extraction. The novelty of the approach is that the 3D-printing is used for the simultaneous printing of the porous retentive b... Read More about Fused deposition modeling based 3D-printing of solid phase cartridges: development and implementation.

Synergism between bisphenol a exposure and overweight/obesity in increasing the malignancy risk in a cohort of patients with thyroid nodules (2022)
Presentation / Conference Contribution
Marotta, V., Grumetto, L., Neri, I., Russo, G., Tortora, A., Izzo, G., Rocco, D., & Vitale, M. Synergism between bisphenol a exposure and overweight/obesity in increasing the malignancy risk in a cohort of patients with thyroid nodules. Presented at European Congress of Endocrinology 2022, Milan, Italy

Introduction: The plasticizer Bisphenol A (BPA) is an endocrine disruptor with thyroid interfering activity. Obesity is a recognized risk factor for thyroid cancer. A recent study showed that subjects with BMI ≥ 25 are more prone to BPA-related thyro... Read More about Synergism between bisphenol a exposure and overweight/obesity in increasing the malignancy risk in a cohort of patients with thyroid nodules.

Comprehensive 2D liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development (2021)
Presentation / Conference Contribution
Russo, G., Grumetto, L., Baert, M., & Lynen, F. (2021, June). Comprehensive 2D liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development. Poster presented at Analytical Research Forum 2021, Royal Society of Chemistry, Online