Exploring the validity of VentriJect Seismofit® for estimating peak oxygen uptake in people with coronary heart disease

Myers, Anna; Ali, Ali; Kudiersky, Nik; Søgaard, Peter; Schmidt, Samuel; Girard, Wilfrid; O’Doherty, Alasdair; Nichols, Simon

Abstract

Background
Peak oxygen uptake ( _ VO2peak) predicts all-cause mortality and can indicate the effectiveness of exercise-based cardiovascular rehabilitation (CR) in people living with coronary heart disease (CHD). Maximal cardiopulmonary exercise testing (CPET), the gold standard method of measuring VO2peak, is expensive, time-consuming, and rarely used in CR. Furthermore, current methods to estimate VO2peak in CR lack accuracy. A promising new device, that uses a quick (5-minute) resting seismocardiography measurement within an algorithm to estimate _ VO2peak, is strongly associated with VO2peak in healthy people (r = .90). However, the validity of VentiJect Seismofit in CHD has not been investigated.

Aim
To explore the validity of the existing Ventriject Seismofit algorithm for predicting VO2peak in people with CHD.

Methods
Between August and November 2022, up to 24 participants aged 18 years, with a history of CHD and currently enrolled in community-based phase IV CR will be recruited. Participants will have their _ VO2peak estimated using the VentriJect Seismofit (twice 20 minutes apart to assess repeatability), complete a maximal CPET on a cycle ergometer followed by a brief questionnaire about their experience of participating in a maximal CPET, and the VentriJect Seismofit device measurement.

Results
Results from this study will be used to assess the validity of the current VentriJect Seismofit algorithm, for estimating VO2peak in individuals with CHD. It will also assess the repeatability of the VentriJect Seismofit VO2peak estimate in this population. Qualitative feedback will provide insight into participants perceptions of participating in a maximal CPET and having VO2 peak measurements taken by VentriJect Seismofit.

Conclusion
Data from this exploratory validation study will support future grant application to conduct a definitive validation study in people with CHD. If the device is demonstrated to provide an accurate and reliable estimate of VO2peak in this population, it would represent a convenient and cost effective method to be widely implemented in cardiac rehabilitation programmes.

Citation

Myers, A., Ali, A., Kudiersky, N., Søgaard, P., Schmidt, S., Girard, W., O’Doherty, A., & Nichols, S. (2022, October). Exploring the validity of VentriJect Seismofit® for estimating peak oxygen uptake in people with coronary heart disease. Presented at BACPR Annual Conference, Birmingham, UK

• Presentation Conference Type: Conference Abstract
• Conference Name: BACPR Annual Conference
• Start Date: Oct 6, 2022
• End Date: Oct 7, 2022
• Acceptance Date: Nov 1, 2022
• Online Publication Date: Nov 21, 2022
• Publication Date: 2022-11
• Deposit Date: Jan 6, 2025
• Print ISSN: 1355-6037
• Electronic ISSN: 1468-201X
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 108
• Issue: Suppl 4
• Article Number: A10
• DOI: https://doi.org/10.1136/heartjnl-2022-bacpr.18