Dr Shufan Yang S.Yang@napier.ac.uk
Associate
A Learning-Based Microultrasound System for the Detection of Inflammation of the Gastrointestinal Tract
Yang, Shufan; Lemke, Christina; Cox, Benjamin Forbes; Newton, Ian P.; N�thke, Inke; Cochran, Sandy
Authors
Christina Lemke
Benjamin Forbes Cox
Ian P. Newton
Inke N�thke
Sandy Cochran
Abstract
Inflammation of the gastrointestinal (GI) tract accompanies several diseases, including Crohn's disease. Currently, video capsule endoscopy and deep bowel enteroscopy are the main means for direct visualisation of the bowel surface. However, the use of optical imaging limits visualisation to the luminal surface only, which makes earlystage diagnosis difficult. In this study, we propose a learning enabled microultrasound (μUS) system that aims to classify inflamed and non-inflamedbowel tissues. μUS images of the caecum, small bowel and colon were obtained from mice treated with agents to induce inflammation. Those images were then used to train three deep learning networks and to provide a ground truth of inflammation status. The classification accuracy was evaluated using 10-fold evaluation and additional B-scan images. Our deep learning approach allowed robust differentiation between healthy tissue and tissue with early signs of inflammation that is not detectable by current endoscopic methods or by human inspection of the μUS images. The methods may be a foundation for future early GI disease diagnosis and enhanced management with computer-aided imaging.
Journal Article Type | Article |
---|---|
Acceptance Date | Sep 1, 2020 |
Online Publication Date | Sep 3, 2020 |
Publication Date | 2021-01 |
Deposit Date | Feb 17, 2021 |
Journal | IEEE Transactions on Medical Imaging |
Print ISSN | 0278-0062 |
Electronic ISSN | 1558-254X |
Publisher | Institute of Electrical and Electronics Engineers |
Peer Reviewed | Peer Reviewed |
Volume | 40 |
Issue | 1 |
Pages | 38-47 |
DOI | https://doi.org/10.1109/tmi.2020.3021560 |
Keywords | Computer-aided detection and diagnosis, gastrointestinal tract, ultrasound, neural network |
Public URL | http://researchrepository.napier.ac.uk/Output/2744621 |
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