Jack Manchester
Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA
Manchester, Jack; Bassani, Dario M; Duprey, Jean-Louis H A; Giordano, Luciana; Vyle, Joseph S; Zhao, Zheng-yun; Tucker, James H R
Authors
Dario M Bassani
Jean-Louis H A Duprey
Luciana Giordano
Joseph S Vyle
Dr John Zhao J.Zhao@napier.ac.uk
Principal Research Fellow
James H R Tucker
Abstract
Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the
number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.
Citation
Manchester, J., Bassani, D. M., Duprey, J. H. A., Giordano, L., Vyle, J. S., Zhao, Z., & Tucker, J. H. R. (2012). Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA. Journal of the American Chemical Society, 134, 10791-10794. https://doi.org/10.1021/ja304205m
Journal Article Type | Article |
---|---|
Publication Date | 2012 |
Deposit Date | Apr 10, 2014 |
Print ISSN | 0002-7863 |
Electronic ISSN | 1520-5126 |
Publisher | American Chemical Society |
Peer Reviewed | Peer Reviewed |
Volume | 134 |
Pages | 10791-10794 |
DOI | https://doi.org/10.1021/ja304205m |
Keywords | Modified DNA strands; light-induced reaction; intramolecular photodimerization; photodimers; binding behaviour; |
Public URL | http://researchrepository.napier.ac.uk/id/eprint/6768 |
Publisher URL | http://dx.doi.org/10.1021/ja304205m |
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