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Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA

Manchester, Jack; Bassani, Dario M; Duprey, Jean-Louis H A; Giordano, Luciana; Vyle, Joseph S; Zhao, Zheng-yun; Tucker, James H R


Jack Manchester

Dario M Bassani

Jean-Louis H A Duprey

Luciana Giordano

Joseph S Vyle

Zheng-yun Zhao

James H R Tucker


Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the
number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.


Manchester, J., Bassani, D. M., Duprey, J. H. A., Giordano, L., Vyle, J. S., Zhao, Z., & Tucker, J. H. R. (2012). Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA. Journal of the American Chemical Society, 134, 10791-10794.

Journal Article Type Article
Publication Date 2012
Deposit Date Apr 10, 2014
Print ISSN 0002-7863
Electronic ISSN 1520-5126
Publisher American Chemical Society
Peer Reviewed Peer Reviewed
Volume 134
Pages 10791-10794
Keywords Modified DNA strands; light-induced reaction; intramolecular photodimerization; photodimers; binding behaviour;
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