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Photocontrolled Binding and Binding-Controlled Photochromism within Anthracene-Modified DNA

Manchester, Jack; Bassani, Dario M; Duprey, Jean-Louis H A; Giordano, Luciana; Vyle, Joseph S; Zhao, Zheng-yun; Tucker, James H R

Authors

Jack Manchester

Dario M Bassani

Jean-Louis H A Duprey

Luciana Giordano

Joseph S Vyle

Zheng-yun Zhao

James H R Tucker



Abstract

Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the
number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.

Citation

Manchester, J., Bassani, D. M., Duprey, J.-L. H. A., Giordano, L., Vyle, J. S., Zhao, Z.-Y., & Tucker, J. H. R. (2012). Photocontrolled Binding and Binding-Controlled Photochromism within Anthracene-Modified DNA. Journal of the American Chemical Society, 134(26), 10791-10794. https://doi.org/10.1021/ja304205m

Journal Article Type Article
Online Publication Date Jun 25, 2012
Publication Date Jul 4, 2012
Deposit Date Apr 10, 2014
Journal Journal of the American Chemical Society
Print ISSN 0002-7863
Electronic ISSN 1520-5126
Publisher American Chemical Society
Peer Reviewed Peer Reviewed
Volume 134
Issue 26
Pages 10791-10794
DOI https://doi.org/10.1021/ja304205m
Keywords Modified DNA strands; light-induced reaction; intramolecular photodimerization; photodimers; binding behaviour
Public URL http://researchrepository.napier.ac.uk/id/eprint/6768



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