Outputs (55)

Accelerating the development of a psychological intervention to restore treatment decision-making capacity in patients with schizophrenia-spectrum disorder: a study protocol for a multi-site, assessor-blinded, pilot Umbrella trial (the DEC:IDES trial) (2023)
Journal Article
Hutton, P., Kelly, J., Taylor, C. D., Williams, B., Emsley, R., Alexander, C. H., …Woodrow, A. (2023). Accelerating the development of a psychological intervention to restore treatment decision-making capacity in patients with schizophrenia-spectrum dis

Background: A high proportion of patients diagnosed with schizophrenia-spectrum disorders will at some point in their lives be assessed as not having the capacity to make their own decisions about pharmacological treatment or inpatient care (‘capaci... Read More about Accelerating the development of a psychological intervention to restore treatment decision-making capacity in patients with schizophrenia-spectrum disorder: a study protocol for a multi-site, assessor-blinded, pilot Umbrella trial (the DEC:IDES trial).

Discerning the adverse effects of psychological therapy: consensus between experts by experience and therapists (2021)
Journal Article
McGlanaghy, E., Jackson, J., Morris, P., Prentice, W., Dougall, N., & Hutton, P. (2022). Discerning the adverse effects of psychological therapy: consensus between experts by experience and therapists. Clinical Psychology and Psychotherapy, 29(2), 579-589

Measurement of adverse effects of psychological therapy is inconsistent due to ambiguity about the concept. The perspective of people undertaking psychological therapy (that is, experts by experience) has largely been overlooked. This study will inve... Read More about Discerning the adverse effects of psychological therapy: consensus between experts by experience and therapists.

A network meta-analysis of psychological interventions for schizophrenia and psychosis: impact on symptoms (2021)
Journal Article
Mc Glanaghy, E., Turner, D., Davis, G. A., Sharpe, H., Dougall, N., Morris, P., Prentice, W., & Hutton, P. (2021). A network meta-analysis of psychological interventions for schizophrenia and psychosis: impact on symptoms. Schizophrenia Research, 228, htt

Background: Evidence for the effectiveness of psychological interventions for schizophrenia/psychosis is growing, however there is no consensus on the psychological intervention most likely to reduce symptoms. Methods: A network meta-analysis was... Read More about A network meta-analysis of psychological interventions for schizophrenia and psychosis: impact on symptoms.

Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis (2019)
Journal Article
Karatzias, T., Murphy, P., Cloitre, M., Bisson, J., Roberts, N., Shevlin, M., …Hutton, P. (2019). Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis. Psychological Medicine, 49(11), 1761-1775. https://doi.o

Background: The 11th revision to the WHO International Classification of Diseases (ICD-11) identified Complex Posttraumatic Stress Disorder (CPTSD) as a new condition. There is a pressing need to identify effective CPTSD interventions. Methods: We co... Read More about Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis.

Cognitive behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT (2019)
Journal Article
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., …Kingdon, D. (2019). Cognitive behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT. Health Technology Assessment, 23(7), 1-144. https://doi.org/1

Background: Clozapine (clozaril, Mylan Products Ltd) is a first-choice treatment for people withschizophrenia who have a poor response to standard antipsychotic medication. However, a significant number of patients who trial clozapine have an inadequ... Read More about Cognitive behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT.

A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications (2018)
Journal Article
Paterson, C., Karatzias, T., Harper, S., Dougall, N., Dickson, A., & Hutton, P. (2019). A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implication

Objectives Acute psychiatric inpatient wards are characterised by minimal provision of therapeutic activities and high readmission rates. Implementation of a comprehensive inpatient psychological intervention service has been recommended to overcome... Read More about A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications.

Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms? (2018)
Journal Article
Hutton, P., Di Rienzo, F., Turkington, D., Spencer, H., & Taylor, P. (2019). Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?. Schizop

Between 5 and 10 percent of people with psychosis will die by suicide, a rate which is 20 to 75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals... Read More about Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?.

The paranoia as defence model of persecutory delusions: a systematic review and meta-analysis (2018)
Journal Article
Murphy, P., Bentall, R. P., Freeman, D., O'Rourke, S., & Hutton, P. (2018). The paranoia as defence model of persecutory delusions: a systematic review and meta-analysis. Lancet Psychiatry, 5(11), 913-929. https://doi.org/10.1016/S2215-0366%2818%2930339-0

Background An influential psychological model of persecutory delusions proposed they are caused by a bias towards holding others responsible for negative events, which serves to prevent underlying low self-esteem from reaching awareness. An early (1... Read More about The paranoia as defence model of persecutory delusions: a systematic review and meta-analysis.

The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis (2018)
Journal Article
Turner, D. T., MacBeth, A., Larkin, A., Moritz, S., Livingstone, K., Campbell, A., & Hutton, P. (2019). The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediati

Background Evidence-based psychological interventions to support treatment decision-making capacity (‘capacity’) in psychosis do not currently exist. This study sought to establish whether reducing the extent to which this group form conclusions bas... Read More about The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis.

Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks (2018)
Journal Article
Woodrow, A., Sparks, S., Bobrovskaia, V., Paterson, C., Murphy, P., & Hutton, P. (2019). Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambr

To identify factors which may help or hinder decision-making ability in people with psychosis, we did a systematic review and meta-analysis of their performance on the Iowa and Cambridge Gambling Tasks. Analysis of 47 samples found they had moderatel... Read More about Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks.