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Outputs (261)

Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis (2021)
Journal Article
Mellis, D., Staines, K. A., Peluso, S., Georgiou, I. C., Dora, N., Kubiak, M., van’t Hof, R., Grillo, M., Farquharson, C., Kinsella, E., Thornburn, A., Ralston, S. H., Salter, D. M., Riobo-Del Galdo, N. A., Hill, R. E., & Ditzel, M. (2021). Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis. PLOS Genetics, 17(4), Article e1009275. https://doi.org/10.1371/journal.pgen.1009275

Mammalian Hedgehog (HH) signalling pathway plays an essential role in tissue homeostasis and its deregulation is linked to rheumatological disorders. UBR5 is the mammalian homologue of the E3 ubiquitin-protein ligase Hyd, a negative regulator of the... Read More about Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis.

Coaches Round table - DB's (2021)
Digital Artefact
Laird, P. (2021). Coaches Round table - DB's. [YouTube]

A round table discussion with Great Britain national coaches discussing Defensive Back play

Prolonged activity of a recombinant manganese superoxide dismutase through a formulation of polymeric multi-layer nanoassemblies targeting cancer cells (2021)
Journal Article
Russo, G., Iaccarino, G., Piccolo, M., Ferraro, M. G., Vecchione, R., Grumetto, L., Netti, P. A., & Santamaria, R. (2021). Prolonged activity of a recombinant manganese superoxide dismutase through a formulation of polymeric multi-layer nanoassemblies targeting cancer cells. European Journal of Pharmaceutical Sciences, 162, Article 105825. https://doi.org/10.1016/j.ejps.2021.105825

A new isoform of human manganese superoxide dismutase (SOD) has been recently isolated and obtained in a synthetic recombinant form and termed rMnSOD. As compared to other SODs, this isoform exhibits a dramatically improved cellular uptake and an int... Read More about Prolonged activity of a recombinant manganese superoxide dismutase through a formulation of polymeric multi-layer nanoassemblies targeting cancer cells.

The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy (2021)
Journal Article
Russo, G., Laneri, S., Di Lorenzo, R., Ferrara, L., & Grumetto, L. (2021). The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy. Water Environment Research, 93(10), 1944-1958. https://doi.org/10.1002/wer.1566

Endocrine disrupting chemicals (EDCs) are agents able to exert perturbation toward the endocrine system via a broad array of signalling pathways. Some EDCs are released into the environment as a result of antropogenic activities. Analytical surveilla... Read More about The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy.

Foresee the glory and train better: Narcissism, goal-setting and athlete training (2021)
Journal Article
Zhang, S., Roberts, R., Woodman, T., Pitkethly, A., English, C., & Nightingale, D. (2021). Foresee the glory and train better: Narcissism, goal-setting and athlete training. Sport, Exercise, and Performance Psychology, 10(3), 381-393. https://doi.org/10.1037/spy0000264

Grandiose narcissism may be debilitative to athlete training because the opportunity for self-enhancement that motivates narcissists to strive is normally absent in training environments. However, this view ignores the divergent influences of the sel... Read More about Foresee the glory and train better: Narcissism, goal-setting and athlete training.

Analytics in Football (2021)
Digital Artefact
Laird, P. (2021). Analytics in Football. [YouTube]

A round table discussion with sports analysts and coaches on the current development and application of analytics in Football.

Research in football: evolving and lessons we can learn from our mistakes (2021)
Journal Article
McCall, A. (2021). Research in football: evolving and lessons we can learn from our mistakes. Science and Medicine in Football, 5(2), https://doi.org/10.1080/24733938.2021.1899275

Background: Football is evolving in many ways, including technical and physical demands as well as the scientific research underpinning and providing many recommendations to practitioners on how to optimise performance of players and by default, team... Read More about Research in football: evolving and lessons we can learn from our mistakes.

Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity (2021)
Journal Article
Niccoli, T., Kerr, F., Snoeren, I., Fabian, D., Aleyakpo, B., Ivanov, D., Sofola-Adesakin, O., Cryar, A., Adcott, J., Thornton, J., & Partridge, L. (2021). Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity. Brain Communications, 3(2), Article fcab053. https://doi.org/10.1093/braincomms/fcab053

Accumulation of amyloid beta peptides is thought to initiate the pathogenesis of Alzheimer’s disease. However, the precise mechanisms mediating their neurotoxicity are unclear. Our microarray analyses show that, in Drosophila models of amyloid beta 4... Read More about Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity.

Measurement of Heart Rate Using the Polar OH1 and Fitbit Charge 3 Wearable Devices in Healthy Adults During Light, Moderate, Vigorous, and Sprint-Based Exercise: Validation Study (2021)
Journal Article
Muggeridge, D. J., Hickson, K., Davies, A. V., Giggins, O. M., Megson, I. L., Gorely, T., & Crabtree, D. R. (2021). Measurement of Heart Rate Using the Polar OH1 and Fitbit Charge 3 Wearable Devices in Healthy Adults During Light, Moderate, Vigorous, and Sprint-Based Exercise: Validation Study. JMIR mHealth and uHealth, 9(3), Article e25313. https://doi.org/10.2196/25313

Background: Accurate, continuous heart rate measurements are important for health assessment, physical activity, and sporting performance, and the integration of heart rate measurements into wearable devices has extended its accessibility. Although t... Read More about Measurement of Heart Rate Using the Polar OH1 and Fitbit Charge 3 Wearable Devices in Healthy Adults During Light, Moderate, Vigorous, and Sprint-Based Exercise: Validation Study.