Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe
(2011)
Journal Article
Duprey, J. H. A., Zhao, Z., Bassani, D. M., Manchester, J., Vyle, J. S., & Tucker, J. H. R. (2011). Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe. Chemical Communications, 47, 6629. https://doi.org/10.1039/c1cc11205h
A fluorescent DNA probe containing an anthracene group attached via an anucleosidic linker can identify all four DNA bases at a single site as well as the epigenetic modification C/5-MeCvia a hybridisation sensing assay.