Uptake of99mTc-exametazime shown by single photon emission computerized tomography in obsessive-compulsive disorder compared with major depression and normal controls (1994)
Journal Article
Edmonstone, Y., Austin, M., Prentice, N., Dougall, N., Freeman, C. P. L., Ebmeier, K. P. & Goodwin, G. M. (1994). Uptake of99mTc-exametazime shown by single photon emission computerized tomography in obsessive-compulsive disorder compared with major depression and normal controls. Acta psychiatrica Scandinavica. 90. (4). 298-303. doi:10.1111/j.1600-0447.1994.tb01597.x. ISSN 0001-690X.

Twelve patients with obsessive-compulsive disorder (OCD) were investigated at rest using single photon emission computerized tomography with 99mTc-exametazime. The uptake of 99mTc-exametazime was expressed relative to calcarine/occipital cortex. Pati... Read More about Uptake of99mTc-exametazime shown by single photon emission computerized tomography in obsessive-compulsive disorder compared with major depression and normal controls.

PASAT performance and the pattern of uptake of 99mTc-exametazime in brain estimated with single photon emission tomography. (1994)
Journal Article
Deary, I. J., Ebmeier, K. P., MacLeod, K. M., Dougall, N., Hepburn, D. A., Frier, B. M. & Goodwin, G. M. (1994). PASAT performance and the pattern of uptake of 99mTc-exametazime in brain estimated with single photon emission tomography. Biological Psychology. 38. (1). 1-18. doi:10.1016/0301-0511(94)90046-9. ISSN 0301-0511.

The effect of the paced auditory serial addition test (PASAT) on the regional uptake of 99mTc-exametazime was determined by single photon emission computed tomography. Twenty insulin-treated diabetic outpatients were scanned at rest and during the pe... Read More about PASAT performance and the pattern of uptake of 99mTc-exametazime in brain estimated with single photon emission tomography..

Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis (1994)
Journal Article
Hicks, A. A., Bailey, M. E., Riley, B. P., Kamphuis, W., Siciliano, M. J., Johnson, K. J., & Darlison, M. G. (1994). Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis. Genomics, 20(2), 285-288. https://doi.org/10.1006/geno.1994.1167

GABAA receptors are hetero-oligomeric ion-channel complexes that are composed of combinations of α, β, γ, and δ subunits and play a major role in inhibitory neurotransmission in the mammalian brain. We report here a microsatellite polymorphism within... Read More about Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis.

Regional cerebral blood flow in IDDM patients: effects of diabetes and of recurrent severe hypoglycaemia (1994)
Journal Article
MacLeod, K. M., Hepburn, D. A., Deary, I. J., Goodwin, G. M., Dougall, N., Ebmeier, K. P. & Frier, B. M. (1994). Regional cerebral blood flow in IDDM patients: effects of diabetes and of recurrent severe hypoglycaemia. Diabetologia. 37. (3). 257-263. doi:10.1007/s001250050103. ISSN 0012-186X.

Chronic hyperglycaemia and recurrent severe hypoglycaemia have both been implicated as causing cerebral damage in patients with diabetes. Although cognitive dysfunction and intellectual impairment have been demonstrated in patients with recurrent sev... Read More about Regional cerebral blood flow in IDDM patients: effects of diabetes and of recurrent severe hypoglycaemia.

Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis (1994)
Journal Article
Moffoot, A., O'Carroll, R. E., Murray, C., Dougall, N., Ebmeier, K. & Goodwin, G. M. (1994). Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis. Psychological Medicine. 24. (01). 53. doi:10.1017/s0033291700026829. ISSN 0033-2917.

The effects upon regional brain function of infusing either saline or clonidine (1·5μg/kg) has been examined in 18 patients with alcoholic Korsakoff's psychosis using 99mTc-hexamethylpropyleneamineoxime (99mTc-HMPAO or 99mTc-Exametazime) and Single P... Read More about Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis.

Short-term effects of electroconvulsive treatment on the uptake of99mTc-Exametazime into brain in major depression shown with single photon emission tomography (1994)
Journal Article
Scott, A. I. F., Dougall, N., Ross, M., O'Carroll, R. E., Riddle, W., Ebmeier, K. P. & Goodwin, G. M. (1993). Short-term effects of electroconvulsive treatment on the uptake of99mTc-Exametazime into brain in major depression shown with single photon emission tomography. Journal of Affective Disorders. 30. (1). 27-34. doi:10.1016/0165-0327(94)90148-1. ISSN 0165-0327.

Fifteen patients with major depression who were being treated with bilateral electroconvulsive treatment (ECT) were investigated before and 45 min after a single ECT using split-dose Single Photon Emission Tomography (SPET or SPECT) with 99mTc-Examet... Read More about Short-term effects of electroconvulsive treatment on the uptake of99mTc-Exametazime into brain in major depression shown with single photon emission tomography.