Biomaterial Risk Management

Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials (2022)
Journal Article
Martin, S., de Haan, L., Miro Estruch, I., Eder, K. M., Marzi, A., Schnekenburger, J., Blosi, M., Costa, A., Antonello, G., Bergamaschi, E., Riganti, C., Beal, D., Carrière, M., Taché, O., Hutchison, G., Malone, E., Young, L., Campagnolo, L., La Civita, F., Pietroiusti, A., …Bouwmeester, H. (2022). Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials. Frontiers in Toxicology, 4, Article 974429. https://doi.org/10.3389/ftox.2022.974429

Engineered nanomaterials have been found to induce oxidative stress. Cellular oxidative stress, in turn, can result in the induction of antioxidant and detoxification enzymes which are controlled by the nuclear erythroid 2-related factor 2 (NRF2) tra... Read More about Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials.

Male Reproductive Health and Advanced Bio-Nanomaterials: A focus on developing predictive assessment methods (2021)
Presentation / Conference Contribution
Horgan, S. L., Young, L., Malone, E., & Hutchison, G. R. (2021, April). Male Reproductive Health and Advanced Bio-Nanomaterials: A focus on developing predictive assessment methods. Poster presented at NanoTox 2021, Online

Assessing the toxicity of engineered nanomaterials in the male reproductive system: Developing an improved testing strategy for hazard assessment (2021)
Presentation / Conference Contribution
Ross, B. L., Malone, E., Rae, M. T., Bouwmeester, H., van der Zande, M., & Hutchison, G. R. (2021, April). Assessing the toxicity of engineered nanomaterials in the male reproductive system: Developing an improved testing strategy for hazard assessment. Poster presented at NanoTox 2021, Online