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Dr Kasia Siemienowicz's Outputs (7)

Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life (2019)
Presentation / Conference Contribution
Siemienowicz, K., Filis, P., Shaw, S., Douglas, A., Thomas, J., Howie, F., Fowler, P., Duncan, C., & Rae, M. (2019, May). Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life. Presented at 21st European Congress of Endocrinology, Lyon, France

Introduction: Adult male offspring of women with PCOS have increased dyslipidaemia, characterised by elevated triglycerides (TG), increased total and LDL-cholesterol (LDL-C), and hyperinsulinaemia. As altered intrauterine endocrine environments can ‘... Read More about Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life.

Exaggerated metabolic changes during puberty precede adult obesity and hyperlipidemia in an ovine model of Polycystic Ovary Syndrome (PCOS) (2016)
Presentation / Conference Contribution
Siemienowicz, K., Coukan, F., Lerner, A., Franks, S., Rae, M., & Duncan, C. (2016, July). Exaggerated metabolic changes during puberty precede adult obesity and hyperlipidemia in an ovine model of Polycystic Ovary Syndrome (PCOS). Paper presented at Society for Reproduction and Fertility Annual Conference, Winchester

Altered adipocytes in an ovine model of polycystic ovary syndrome (2015)
Presentation / Conference Contribution
Siemienowicz, K., Couckan, F., Lerner, A., Franks, S., Rae, M., & Duncan, C. (2015, November). Altered adipocytes in an ovine model of polycystic ovary syndrome. Poster presented at Society for Endocrinology BES, Edinburgh

Obesity in PCOS: a consequence of prenatally programmed reduced energy expenditure (2015)
Presentation / Conference Contribution
Siemienowicz, K., Rae, M., Lerner, A., Franks, S., & Duncan, C. (2015, July). Obesity in PCOS: a consequence of prenatally programmed reduced energy expenditure. Paper presented at Society for Reproduction and Fertility Annual Conference

Polycystic ovary syndrome, a common endocrine condition affecting up to 10% of women of reproductive age, is associated with an increased risk of developing insulin resistance and obesity. Obesity is associated with increased energy intake or reduced... Read More about Obesity in PCOS: a consequence of prenatally programmed reduced energy expenditure.

The pathophysiology of increased hepatic IGF1 expression in an ovine model of polycystic ovary syndrome (2014)
Presentation / Conference Contribution
Siemienowicz, K., Boswell, L., Carr, D., Mina, T., Connolly, F., Rae, M., & Duncan, C. (2014, May). The pathophysiology of increased hepatic IGF1 expression in an ovine model of polycystic ovary syndrome. Poster presented at 16th European Congress of Endocrinology, Wroclaw, Poland

Exposure of pregnant sheep to increased concentrations of testosterone during midgestation results in a PCOS-like condition in the female offspring that includes increased hepatic IGF1. The aim of this study was to investigate the molecular pathophys... Read More about The pathophysiology of increased hepatic IGF1 expression in an ovine model of polycystic ovary syndrome.