Absence of mutations in sites of key functional importance of the RIα and RIIβ regulatory subunits of protein kinase A in human breast cancers
(1998)
Journal Article
Phillips, H., MacCallum, J., Burns, D., Cho-Chung, Y., & Miller, W. (1998). Absence of mutations in sites of key functional importance of the RIα and RIIβ regulatory subunits of protein kinase A in human breast cancers. The Breast, 7(3), 139-142. https://doi.org/10.1016/s0960-9776%2898%2990024-8
There is evidence that the regulatory subunits (R) of cyclic AMP-dependent protein kinase A (PKA) are important in the biology of breast cancer and that mutations of both RIα and RIIβ, alter cellular behaviour. Consequently, a PCR-SSCP assay was esta... Read More about Absence of mutations in sites of key functional importance of the RIα and RIIβ regulatory subunits of protein kinase A in human breast cancers.