Dr Janis MacCallum's Outputs (2)

Changes in expression of transforming growth factor beta mRNA isoforms in patients undergoing tamoxifen therapy (1996)
Journal Article
MacCallum, J., Keen, J., Bartlett, J., Thompson, A., Dixon, J., & Miller, W. (1996). Changes in expression of transforming growth factor beta mRNA isoforms in patients undergoing tamoxifen therapy. British Journal of Cancer, 74(3), 474-478. https://doi.org/10.1038/bjc.1996.385

Tumour was obtained from 37 patients with oestrogen receptor-positive breast cancer, before and during treatment with tamoxifen, and examined qualitatively and semi-qualitatively for mRNA of the three mammalian TGF-beta isoforms. Levels of TGF-beta i... Read More about Changes in expression of transforming growth factor beta mRNA isoforms in patients undergoing tamoxifen therapy.

Solid-phase extraction and high-performance liquid chromatographic determination of tamoxifen and its major metabolites in plasma (1996)
Journal Article
MacCallum, J., Cummings, J., Dixon, J., & Miller, W. (1996). Solid-phase extraction and high-performance liquid chromatographic determination of tamoxifen and its major metabolites in plasma. Journal of Chromatography B, 678(2), 317-323. https://doi.org/10.1016/0378-4347%2895%2900530-7

Tamoxifen (TAM) is a triphenylethylene anti-oestrogen, commonly used in the treatment of breast cancer. Patients receiving tamoxifen therapy may experience both de novo and acquired resistance. As one of the mechanisms for this may be extensive perip... Read More about Solid-phase extraction and high-performance liquid chromatographic determination of tamoxifen and its major metabolites in plasma.