Concentration of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours
(2000)
Journal Article
MacCallum, J., Cummings, J., Dixon, J. M., & Miller, W. R. (2000). Concentration of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours. Nature, 82(10), 1629-1635. https://doi.org/10.1054/bjoc.2000.1120
Patients treated with tamoxifen (TAM) for primary breast cancer often manifest de novo or acquired resistance, possibly through changes in drug metabolism. Using solid-phase extraction methods and reversed-phase high-performance liquid chromatography... Read More about Concentration of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours.