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Variability in nitrate-reducing oral bacteria and nitric oxide metabolites in biological fluids following dietary nitrate administration: An assessment of the critical difference (2018)
Journal Article
Liddle, L., Burleigh, M. C., Monaghan, C., Muggeridge, D. J., Sculthorpe, N., Pedlar, C. R., …Easton, C. (2019). Variability in nitrate-reducing oral bacteria and nitric oxide metabolites in biological fluids following dietary nitrate administration: An

There is conflicting evidence on whether dietary nitrate supplementation can improve exercise performance. This may arise from the complex nature of nitric oxide (NO) metabolism which causes substantial inter-individual variability, within-person bio... Read More about Variability in nitrate-reducing oral bacteria and nitric oxide metabolites in biological fluids following dietary nitrate administration: An assessment of the critical difference.

To clot or not to clot? That is a free radical question (2018)
Journal Article
Crabtree, D. R., Muggeridge, D., Leslie, S. J., Megson, I. L., & Cobley, J. N. (2018). To clot or not to clot? That is a free radical question. Journal of Physiology, 596(20), 4805-4806. https://doi.org/10.1113/jp276786

nravelling the biological roles of reactive oxygen species (ROS) is challenging (Murphy et al. 2011). There are three key challenges: (1) the global term ‘ROS’ subsumes chemically diverse free radical and non‐radical species making it difficult to at... Read More about To clot or not to clot? That is a free radical question.

Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria (2018)
Journal Article
Burleigh, M. C., Liddle, L., Monaghan, C., Muggeridge, D. J., Sculthorpe, N., Butcher, J. P., …Easton, C. (2018). Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria. Free Radical Biology and

Nitric oxide (NO) can be generated endogenously via NO synthases or via the diet following the action of symbiotic nitrate-reducing bacteria in the oral cavity. Given the important role of NO in smooth muscle control there is an intriguing suggestion... Read More about Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria.

The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes (2018)
Journal Article
Monaghan, C., McIlvenna, L. C., Liddle, L., Burleigh, M., Weller, R. B., Fernandez, B. O., …Easton, C. (2018). The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes. European Journa

PURPOSE: The present study investigated different doses of ultraviolet-A (UV-A) light on plasma nitric oxide metabolites and cardiorespiratory variables. METHODS: Ten healthy male participants completed three experimental conditions, 7 days apart.... Read More about The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes.

Untargeted Metabolomics Profiling of an 80.5 km Simulated Treadmill Ultramarathon (2018)
Journal Article
Howe, C. C., Alshehri, A., Muggeridge, D., Mullen, A., Boyd, M., Spendiff, O., …Watson, D. (2018). Untargeted Metabolomics Profiling of an 80.5 km Simulated Treadmill Ultramarathon. Metabolites, 8(1), Article 14. https://doi.org/10.3390/metabo8010014

Metabolomic profiling of nine trained ultramarathon runners completing an 80.5 km self-paced treadmill-based time trial was carried out. Plasma samples were obtained from venous whole blood, collected at rest and on completion of the distance (post-8... Read More about Untargeted Metabolomics Profiling of an 80.5 km Simulated Treadmill Ultramarathon.