TLE1 modifies the effects of NOD2 in the pathogenesis of Crohn's Disease
(2011)
Journal Article
Nimmo, E. R., Stevens, C., Phillips, A. M., Smith, A., Drummond, H. E., Noble, C. L., …Satsangi, J. (2011). TLE1 modifies the effects of NOD2 in the pathogenesis of Crohn's Disease. Gastroenterology, 141(3), 972-981.e2. https://doi.org/10.1053/j.gastro.
Background & Aims The mechanisms by which specific mutations in NOD2/CARD15 increase the risk for Crohn's disease (CD) are unclear. We identified proteins that interact with {NOD2} and investigated them by expression, genetic, and functional analyses... Read More about TLE1 modifies the effects of NOD2 in the pathogenesis of Crohn's Disease.