All Outputs (4)

Expression of secretory leukocyte protease inhibitor and elafin in human fallopian tube and in an in-vitro model of Chlamydia trachomatis infection (2008)
Journal Article
King, A. E., Wheelhouse, N., Cameron, S., McDonald, S. E., Lee, K., Entrican, G., …Horne, A. W. (2009). Expression of secretory leukocyte protease inhibitor and elafin in human fallopian tube and in an in-vitro model of Chlamydia trachomatis infection. Human Reproduction, 24(3), 679-686. https://doi.org/10.1093/humrep/den452

BACKGROUND: Secretory leukocyte protease inhibitor (SLPI) and elafin are anti-protease and anti-microbial molecules with a role in innate immune defence. They have been demonstrated at multiple mucosal surfaces including those of the female reproduct... Read More about Expression of secretory leukocyte protease inhibitor and elafin in human fallopian tube and in an in-vitro model of Chlamydia trachomatis infection.

Pregnancy, indoleamine 2,3-dioxygenase (IDO) and chlamydial abortion: an unresolved paradox (2008)
Journal Article
Entrican, G., Wattegedera, S., Rocchi, M., & Wheelhouse, N. (2009). Pregnancy, indoleamine 2,3-dioxygenase (IDO) and chlamydial abortion: an unresolved paradox. Veterinary Microbiology, 135(1-2), 98-102. https://doi.org/10.1016/j.vetmic.2008.09.028

Chlamydophila abortus infects the placental trophoblast in sheep, humans and mice, causing cell damage and inflammation that culminates in abortion. Host control of C. abortus appears to be heavily dependant on interferon (IFN)-gamma production. IFN-... Read More about Pregnancy, indoleamine 2,3-dioxygenase (IDO) and chlamydial abortion: an unresolved paradox.

Molecular detection of Chlamydophila abortus in post-abortion sheep at oestrus and subsequent lambing (2008)
Journal Article
Livingstone, M., Wheelhouse, N., Maley, S. W., & Longbottom, D. (2009). Molecular detection of Chlamydophila abortus in post-abortion sheep at oestrus and subsequent lambing. Veterinary Microbiology, 135(1-2), 134-141. https://doi.org/10.1016/j.vetmic.200

Enzootic abortion of ewes (EAE), resulting from infection with the bacterium Chlamydophila abortus (C. abortus), is a major cause of lamb loss in Europe. The purpose of this study was to assess the potential impact of the shedding of organisms in pos... Read More about Molecular detection of Chlamydophila abortus in post-abortion sheep at oestrus and subsequent lambing.

Chlamydia trachomatis and Chlamydophila abortus induce the expression of secretory leukocyte protease inhibitor in cells of the human female reproductive tract (2008)
Journal Article
Wheelhouse, N., Wattegedera, S., Fleming, D., Fitch, P., Kelly, R., & Entrican, G. (2008). Chlamydia trachomatis and Chlamydophila abortus induce the expression of secretory leukocyte protease inhibitor in cells of the human female reproductive tract. Microbiology and Immunology, 52(9), 465-468. https://doi.org/10.1111/j.1348-0421.2008.00058.x

C. trachomatis and C. abortus are related Gram-negative intracellular bacteria that cause reproductive failure due to infertility (C. trachomatis) or abortion (C. abortus). These organisms target epithelial cells in the reproductive tract and/or plac... Read More about Chlamydia trachomatis and Chlamydophila abortus induce the expression of secretory leukocyte protease inhibitor in cells of the human female reproductive tract.