All Outputs (187)

Genetic assessment and development of genomic resources for Nubian ibex conservation management in Oman (2024)
Thesis
Al Ghafri, M. K. S. Genetic assessment and development of genomic resources for Nubian ibex conservation management in Oman. (Thesis). Edinburgh Napier University

The Nubian ibex (Capra nubiana) is listed as Vulnerable according to IUCN Red List. It is patchily distributed across parts of Africa and Arabia, including Oman where it is present in isolated populations in central and southern region of the country... Read More about Genetic assessment and development of genomic resources for Nubian ibex conservation management in Oman.

Microplastics in organic waste-derived materials: quantification, and assessment of associated bacterial community and its antimicrobial resistance (2024)
Thesis
Rimmaudo, A. Microplastics in organic waste-derived materials: quantification, and assessment of associated bacterial community and its antimicrobial resistance. (Thesis). Edinburgh Napier University

This study aimed to quantify and characterise microplastics in organic-rich waste materials: biosolids, compost, and anaerobic digestates, and investigate their associated bacterial community and potential role in the spreading of AMR. A cost-effecti... Read More about Microplastics in organic waste-derived materials: quantification, and assessment of associated bacterial community and its antimicrobial resistance.

The interaction of regulatory T-cells and osteoclasts in health and ageing (2024)
Thesis
Lopera-Burgueno, R. The interaction of regulatory T-cells and osteoclasts in health and ageing. (Thesis). Edinburgh Napier University

Regulatory T cells (Tregs) are part of the adaptive immune system, and their main role is to maintain peripheral tolerance. Emerging evidence suggests that Tregs play a key role in regulating healthy bone mass by driving bone repair and regeneration... Read More about The interaction of regulatory T-cells and osteoclasts in health and ageing.

The impact of environmental and cultural factors within a Scottish football club on the motivational attributes of professional footballers and coaches (2024)
Thesis
Collison, L. A. The impact of environmental and cultural factors within a Scottish football club on the motivational attributes of professional footballers and coaches. (Thesis). Edinburgh Napier University

This project aimed to explore the motivational characteristics of individuals working within a Scottish Championship football club, and how they are influenced by the club environment and culture.

Methods: A multi-phase design was used. Phase 1 us... Read More about The impact of environmental and cultural factors within a Scottish football club on the motivational attributes of professional footballers and coaches.

Identification and whole genome analysis of cefotaxime resistant Escherichia coli recovered from a tertiary treatment wastewater treatment plant discharge point (2024)
Thesis
Black, L. Identification and whole genome analysis of cefotaxime resistant Escherichia coli recovered from a tertiary treatment wastewater treatment plant discharge point. (Thesis). Edinburgh Napier University

Wastewater treatment plants (WWTPs) act as reservoirs for antibiotic resistant bacteria (ARB) and may facilitate transmission of antibiotic resistance genes (ARGs) between bacterial populations including pathogens that in turn may persist in wider aq... Read More about Identification and whole genome analysis of cefotaxime resistant Escherichia coli recovered from a tertiary treatment wastewater treatment plant discharge point.

The effects of age and fitness status on circulating angiogenic T-cells (2024)
Thesis
Stephen, L. R. A. The effects of age and fitness status on circulating angiogenic T-cells. (Thesis). Edinburgh Napier University

Advancing age is associated with a decline in immune cell function, both immunological function and potential for immune cells to participate in tissue repair. Discrete subsets of T-cells, such as CD31+ T cells, also known as angiogenic T cells (TANG... Read More about The effects of age and fitness status on circulating angiogenic T-cells.

Development of a novel 3D culture system to understand bone-cartilage crosstalk in osteoarthritis (2024)
Thesis
Hughes, D. J. Development of a novel 3D culture system to understand bone-cartilage crosstalk in osteoarthritis. (Thesis). Edinburgh Napier University

Osteoarthritis (OA) is a chronic degenerative disease of the articulated joint that affects approximately 10% of men and 18% of women over the age of 60 globally. There is no cure for OA, and current treatments aim to attenuate the symptoms e.g., non... Read More about Development of a novel 3D culture system to understand bone-cartilage crosstalk in osteoarthritis.

A critical examination of the values and ethics of Scotland’s Curriculum for Excellence (CfE) (2024)
Thesis
Osborne, T. P. A critical examination of the values and ethics of Scotland’s Curriculum for Excellence (CfE). (Thesis). Edinburgh Napier University

The thesis offers a new perspective through which to analyse CfE, by focusing on values and ethics, and the value pluralism of Isaiah Berlin.

The record suggests CfE is a blended, instrumentalist mix of values and ethics. I argue that ‘joined-up’... Read More about A critical examination of the values and ethics of Scotland’s Curriculum for Excellence (CfE).

Communities of constraint: An ethnographic study of Tibetan refugees navigating protracted displacement and everyday vulnerability in Nepal (2024)
Thesis
Schwartz, K. R. Communities of constraint: An ethnographic study of Tibetan refugees navigating protracted displacement and everyday vulnerability in Nepal. (Thesis). Edinburgh Napier University

Since the beginning of the Tibetan refugee crisis in 1959, discourses surrounding the Tibetan diaspora have emphasized their resilience in the face of hardship and characterized the group as a ‘successful’ refugee population in displacement. This the... Read More about Communities of constraint: An ethnographic study of Tibetan refugees navigating protracted displacement and everyday vulnerability in Nepal.

Characterisation of microbial communities associated with potato cyst nematodes in a suppressive soil and the bicontrol potential of selected isolates (2024)
Thesis
Jones, A. L. Characterisation of microbial communities associated with potato cyst nematodes in a suppressive soil and the bicontrol potential of selected isolates. (Thesis). Edinburgh Napier University

Potato cyst nematodes Globodera pallida and G. rostochiensis (PCN) pose a growing threat to global potato production. As chemical nematicides are increasingly removed from market, novel, environmentally sound methods are needed to manage PCN populati... Read More about Characterisation of microbial communities associated with potato cyst nematodes in a suppressive soil and the bicontrol potential of selected isolates.

Anti-adhesive and anti-biofilm potential of extra-cellular biosurfactants produced by mycolate actinobacteria of the suborder Corynebacterineae against biofilm-forming human pathogens (2024)
Thesis
Hodar, J. H. Anti-adhesive and anti-biofilm potential of extra-cellular biosurfactants produced by mycolate actinobacteria of the suborder Corynebacterineae against biofilm-forming human pathogens. (Thesis). Edinburgh Napier University

Microbial biosurfactants, amphipathic surface-active compounds, are promising candidates for the prevention and control of clinical biofilms and unlike their chemical counterparts exhibit low toxicity and are biodegradable. Members of mycolic acid-co... Read More about Anti-adhesive and anti-biofilm potential of extra-cellular biosurfactants produced by mycolate actinobacteria of the suborder Corynebacterineae against biofilm-forming human pathogens.

Exploring adolescent fast bowling: a mixed methods approach (2023)
Thesis
Hislen, S. Exploring adolescent fast bowling: a mixed methods approach. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/3406802

Introduction: Limited mixed methods research has been conducted into the physical and skills requirements of a developing fast bowler.

Methods: This mixed methods study explored the interrelationship between the physical and skill requirements in... Read More about Exploring adolescent fast bowling: a mixed methods approach.

Analysis of circumstances leading to injuries in elite football players (2023)
Thesis
Aiello, F. Analysis of circumstances leading to injuries in elite football players. (Thesis). Edinburgh Napier University

Understanding injury mechanisms is key to developing prevention strategies. Information concerning injury mechanisms can be obtained by analysing the sportspecific activities during which injuries occur (i.e., inciting circumstances). Despite the rec... Read More about Analysis of circumstances leading to injuries in elite football players.

Design of a new fluorogenic molecular probe of lipases that will be specific for monoacylglycerol lipase (2023)
Thesis
Ajaezu, J. C. Design of a new fluorogenic molecular probe of lipases that will be specific for monoacylglycerol lipase. (Thesis). Edinburgh Napier University

Homeostatic imbalances in enzyme activities have been linked to an array of human pathological conditions. Evidence exists for the role of monoacylglycerol lipase (MAGL) in the development and progression of malignant forms of cancers, including brea... Read More about Design of a new fluorogenic molecular probe of lipases that will be specific for monoacylglycerol lipase.

Design and Development of Novel Targeted Anticancer Drugs (2023)
Thesis
Akpughe, E. Design and Development of Novel Targeted Anticancer Drugs. (Thesis). Edinburgh Napier University

Despite major advances in treatments for cancer, the delivery of small molecule chemotherapeutics to tumour cells selectively and the circumvention of multidrug resistance persist as obstacles that limit their efficacy in the clinical setting. One ap... Read More about Design and Development of Novel Targeted Anticancer Drugs.

An Examination of Talent Identification and Development Systems within Jordanian Football (2023)
Thesis
Altwassi, S. S. An Examination of Talent Identification and Development Systems within Jordanian Football. (Thesis). Edinburgh Napier University

In recent times, the sports sector across the globe has attracted economic interests both from the public and the private sector. For instance, it was estimated that over $14 billion was spent in hosting the FIFA 2018 World Cup in Russia. Also, by so... Read More about An Examination of Talent Identification and Development Systems within Jordanian Football.

Design, Synthesis and Evaluation of Hybrid Intracellularly Targeted Anticancer and Antimicrobial Agents (2023)
Thesis
Aziz, K. Design, Synthesis and Evaluation of Hybrid Intracellularly Targeted Anticancer and Antimicrobial Agents. (Thesis). Edinburgh Napier University

One of the most important barriers to the success of anticancer therapy is the dysregulation of apoptotic pathways that limit effectiveness of current chemotherapy. A long-term objective seeks to exploit links between apoptosis and the functions of m... Read More about Design, Synthesis and Evaluation of Hybrid Intracellularly Targeted Anticancer and Antimicrobial Agents.

An Investigation of Return to Sport Decision Making in Male Professional Football Following Lower Limb Muscle Injury (2023)
Thesis
Dunlop, G. R. An Investigation of Return to Sport Decision Making in Male Professional Football Following Lower Limb Muscle Injury. (Thesis). Edinburgh Napier University

Background: Return to sport (RTS) following muscle injury represents an on-going challenge for professional male football teams. While published expert consensus have provided guidance to practitioners, it is currently not clear if, and what criteria... Read More about An Investigation of Return to Sport Decision Making in Male Professional Football Following Lower Limb Muscle Injury.

An Exploration of an Elite Scottish Football Academy Experience: The Role of Psychological and Environmental Characteristics in Facilitating Success (2023)
Thesis
Elder, K. A. An Exploration of an Elite Scottish Football Academy Experience: The Role of Psychological and Environmental Characteristics in Facilitating Success. (Thesis). Edinburgh Napier University

The nature of the talent development environment, and key psychological attributes of the players themselves (e.g., self-regulated learning) can explain why some players realise their potential and others do not. Therefore, understanding the environm... Read More about An Exploration of an Elite Scottish Football Academy Experience: The Role of Psychological and Environmental Characteristics in Facilitating Success.

A critical exploration of the role, value and culture of police learning in Scotland (2023)
Thesis
Engelmann, L. A critical exploration of the role, value and culture of police learning in Scotland. (Thesis). Edinburgh Napier University

Police Scotland pride themselves on being a ‘learning organisation’ (Police Scotland, 2020a), yet their ability and willingness to develop supportive and effective learning environments has been questioned (HMICS, 2020, 2021). The lack of consensus i... Read More about A critical exploration of the role, value and culture of police learning in Scotland.