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The effects of age and fitness status on circulating angiogenic T-cells (2024)
Thesis
Stephen, L. R. A. The effects of age and fitness status on circulating angiogenic T-cells. (Thesis). Edinburgh Napier University

Advancing age is associated with a decline in immune cell function, both immunological function and potential for immune cells to participate in tissue repair. Discrete subsets of T-cells, such as CD31+ T cells, also known as angiogenic T cells (TANG... Read More about The effects of age and fitness status on circulating angiogenic T-cells.

Microplastics in organic waste-derived materials: quantification, and assessment of associated bacterial community and its antimicrobial resistance (2024)
Thesis
Rimmaudo, A. Microplastics in organic waste-derived materials: quantification, and assessment of associated bacterial community and its antimicrobial resistance. (Thesis). Edinburgh Napier University

This study aimed to quantify and characterise microplastics in organic-rich waste materials: biosolids, compost, and anaerobic digestates, and investigate their associated bacterial community and potential role in the spreading of AMR. A cost-effecti... Read More about Microplastics in organic waste-derived materials: quantification, and assessment of associated bacterial community and its antimicrobial resistance.

The interaction of regulatory T-cells and osteoclasts in health and ageing (2024)
Thesis
Lopera-Burgueno, R. The interaction of regulatory T-cells and osteoclasts in health and ageing. (Thesis). Edinburgh Napier University

Regulatory T cells (Tregs) are part of the adaptive immune system, and their main role is to maintain peripheral tolerance. Emerging evidence suggests that Tregs play a key role in regulating healthy bone mass by driving bone repair and regeneration... Read More about The interaction of regulatory T-cells and osteoclasts in health and ageing.

Impacts of micro- and nanoplastics on early-life health: a roadmap towards risk assessment (2024)
Journal Article
Christopher, E. A., Christopher-de Vries, Y., Devadoss, A., Mandemaker, L. D., van Boxel, J., Copsey, H. M., Dusza, H. M., Legler, J., Meirer, F., Muncke, J., Nawrot, T. S., Saenen, N. D., Scholz-Böttcher, B. M., Tran, L., Weckhuysen, B. M., Zou, R., Zimmermann, L., Galea, K. S., Vermeulen, R., & Boyles, M. S. P. (in press). Impacts of micro- and nanoplastics on early-life health: a roadmap towards risk assessment. Microplastics and Nanoplastics, 4(1), 13. https://doi.org/10.1186/s43591-024-00089-3

Micro- and nanoplastics (MNPs) are ubiquitous environmental pollutants representing a concern for human health. MNPs have been detected in human placentas, indicating that during pregnancy maternal exposure may lead to placental transfer and foetal e... Read More about Impacts of micro- and nanoplastics on early-life health: a roadmap towards risk assessment.

Inspection time and intelligence: A five-wave longitudinal study from age 70 to age 82 in the Lothian Birth Cohort 1936 (2024)
Journal Article
Deary, I. J., Cox, S. R., & Okely, J. A. (2024). Inspection time and intelligence: A five-wave longitudinal study from age 70 to age 82 in the Lothian Birth Cohort 1936. Intelligence, 105, Article 101844. https://doi.org/10.1016/j.intell.2024.101844

To test the idea that the slowing of simple information processing contributes to more general cognitive ageing, it is necessary to demonstrate that changes in the two variables are correlated as people grow older. Here, we examine the association be... Read More about Inspection time and intelligence: A five-wave longitudinal study from age 70 to age 82 in the Lothian Birth Cohort 1936.

Kenyan police use excessive force because they’re serving political elites, not the public – policy analyst (2024)
Digital Artefact
Wairuri, K. (2024). Kenyan police use excessive force because they’re serving political elites, not the public – policy analyst. [Blog post]

Public protests in Kenya have often been criminalised, leading to brutal police crackdowns. This played out in recent protests against the cost of living in Kenya, and amid an attempt by the government to introduce new taxes. The police responded wit... Read More about Kenyan police use excessive force because they’re serving political elites, not the public – policy analyst.

Police officer knowledge of and attitudes to opioid overdose and naloxone administration: an evaluation of police training in Scotland (2024)
Journal Article
Hillen, P., Speakman, E. M., Jamieson, M., Dougall, N., Heyman, I., Murray, J., Aston, E. V., & McAuley, A. (online). Police officer knowledge of and attitudes to opioid overdose and naloxone administration: an evaluation of police training in Scotland. Policing and Society, https://doi.org/10.1080/10439463.2024.2367142

In the context of escalating drug-related deaths, during 2021 Police Scotland implemented a pilot project incorporating naloxone training to test the carriage and administration of naloxone by officers. The current paper presents data from the evalua... Read More about Police officer knowledge of and attitudes to opioid overdose and naloxone administration: an evaluation of police training in Scotland.

Should Job Centres provide career guidance? (2024)
Digital Artefact
Robertson, P. (2024). Should Job Centres provide career guidance?. [Blog]

This article considers the merits of the Labour Party Manifesto proposal to integrate career services into Job Centre Plus services (the UK's public employment service).

Improving the dichloro-dihydro-fluorescein (DCFH) assay for the assessment of intracellular reactive oxygen species formation by nanomaterials (2024)
Journal Article
Ruijter, N., van der Zee, M., Katsumiti, A., Boyles, M., Cassee, F. R., & Braakhuis, H. (2024). Improving the dichloro-dihydro-fluorescein (DCFH) assay for the assessment of intracellular reactive oxygen species formation by nanomaterials. NanoImpact, 35, Article 100521. https://doi.org/10.1016/j.impact.2024.100521

To facilitate Safe and Sustainable by Design (SSbD) strategies during the development of nanomaterials (NMs), quick and easy in vitro assays to test for hazard potential at an early stage of NM development are essential. The formation of reactive oxy... Read More about Improving the dichloro-dihydro-fluorescein (DCFH) assay for the assessment of intracellular reactive oxygen species formation by nanomaterials.

Mangrovimonas cancribranchiae sp. nov., a novel bacterial species associated with the gills of the fiddler crab Cranuca inversa (Brachyura, Ocypodidae) from Red Sea mangroves (2024)
Journal Article
Yang, X., Garuglieri, E., Van Goethem, M. W., Marasco, R., Fusi, M., & Daffonchio, D. (2024). Mangrovimonas cancribranchiae sp. nov., a novel bacterial species associated with the gills of the fiddler crab Cranuca inversa (Brachyura, Ocypodidae) from Red Sea mangroves. International Journal of Systematic and Evolutionary Microbiology, 74(6), https://doi.org/10.1099/ijsem.0.006415

Two bacteria, UG2_1T and UG2_2, were isolated from the gill tissues of the mangrove fiddler crab Cranuca inversa collected on the east coast of the Red Sea (Thuwal, Saudi Arabia). The cells are Gram-negative, rod-shaped, orange-pigmented, motile by g... Read More about Mangrovimonas cancribranchiae sp. nov., a novel bacterial species associated with the gills of the fiddler crab Cranuca inversa (Brachyura, Ocypodidae) from Red Sea mangroves.

Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023 (2024)
Journal Article
Neri, I., Russo, G., & Grumetto, L. (2024). Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023. Archives of Toxicology, 98(8), 2441-2461. https://doi.org/10.1007/s00204-024-03793-4

In this review article, the research works covering the analytical determination of bisphenol A (BPA) and its structural analogues published from 2018 to present (February 2024) were examined. The review offers an overview of the concentration levels... Read More about Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023.

Oxygen supersaturation adds resistance to a cnidarian: Symbiodiniaceae holobiont under moderate warming in experimental settings (2024)
Journal Article
Arossa, S., Klein, S. G., Garuglieri, E., Steckbauer, A., Parry, A. J., Alva Garcia, J. V., Alamoudi, T., Yang, X., Hung, S.-H., Salazar, O. R., Marasco, R., Fusi, M., Aranda, M., Daffonchio, D., & Duarte, C. M. (2024). Oxygen supersaturation adds resistance to a cnidarian: Symbiodiniaceae holobiont under moderate warming in experimental settings. Frontiers in Marine Science, 11, Article 1305674. https://doi.org/10.3389/fmars.2024.1305674

Ocean warming reduces O2 solubility and increases organismal O2 demand, endangering marine life. Coastal ecosystems, however, experience O2 supersaturation during peak daytime temperatures due to metabolic cycles. Recent discoveries show that this en... Read More about Oxygen supersaturation adds resistance to a cnidarian: Symbiodiniaceae holobiont under moderate warming in experimental settings.

From whole bodies to single cells: A guide to transcriptomic approaches for ecology and evolutionary biology (2024)
Journal Article
Hoedjes, K. M., Grath, S., Posnien, N., Ritchie, M. G., Schlötterer, C., Abbott, J. K., Almudi, I., Coronado‐Zamora, M., Durmaz Mitchell, E., Flatt, T., Fricke, C., Glaser‐Schmitt, A., González, J., Holman, L., Kankare, M., Lenhart, B., Orengo, D. J., Snook, R. R., Yılmaz, V. M., & Yusuf, L. (online). From whole bodies to single cells: A guide to transcriptomic approaches for ecology and evolutionary biology. Molecular Ecology, https://doi.org/10.1111/mec.17382

RNA sequencing (RNAseq) methodology has experienced a burst of technological developments in the last decade, which has opened up opportunities for studying the mechanisms of adaptation to environmental factors at both the organismal and cellular lev... Read More about From whole bodies to single cells: A guide to transcriptomic approaches for ecology and evolutionary biology.

Is there a role for neuroscience in career counselling? (2024)
Digital Artefact
Robertson, P., Garden, C., & Carmichael, D. (2024). Is there a role for neuroscience in career counselling?. [Blog post]

This blog post provides a critical perspective on neuroscience informed career counselling.

Surveying Birds in Open Habitats near Proposed Woodland Creation Schemes: What is the Effect of Having Fewer Visits? (2024)
Journal Article
Borthwick, M. D., Kerslake, L., Findlay, M., Briers, R. A., Tomlin, C., Riddle, N., & White, P. J. (2024). Surveying Birds in Open Habitats near Proposed Woodland Creation Schemes: What is the Effect of Having Fewer Visits?. In Practice (CIEEM), 124, 32-37

In relation to new woodland creation in England, the Forestry Commission (FC) may require breeding bird surveys of proposed sites to assess suitability for planting or natural colonisation. Previous protocols required six visits, but we wanted to tes... Read More about Surveying Birds in Open Habitats near Proposed Woodland Creation Schemes: What is the Effect of Having Fewer Visits?.

Design of new anticancer drugs by selectable intracellular organelle targeting: make for the mitochondria or turn left for the lysosome? (2024)
Presentation / Conference Contribution
Mincher, D., Kamel, M., Mohammed, O., MacCallum, J., & Turnbull, A. (2024, June). Design of new anticancer drugs by selectable intracellular organelle targeting: make for the mitochondria or turn left for the lysosome?. Presented at EACR 2024: Innovative Cancer Science, Rotterdam, Netherlands

Introduction
Defining structural features that can control and pinpoint the delivery of drugs to specific sub-cellular organelles ofcancer cells offers the prospect of designing more potentand selective drugs that negate drug resistance, with less d... Read More about Design of new anticancer drugs by selectable intracellular organelle targeting: make for the mitochondria or turn left for the lysosome?.

Identifying how pre-existing resources combine to shape the experiences of work and family life of a diverse sample of working parents with at least one child in primary school in Scotland during COVID-19 pandemic-related social restrictions: a qualitative descriptive design (2024)
Journal Article
McQueen, F., & Osborn, S. (2024). Identifying how pre-existing resources combine to shape the experiences of work and family life of a diverse sample of working parents with at least one child in primary school in Scotland during COVID-19 pandemic-related social restrictions: a qualitative descriptive design. BMJ Open, 14(6), Article e078850. https://doi.org/10.1136/bmjopen-2023-078850

Objectives: This study aimed to identify factors that shaped working parents (WPs’) experiences of COVID-19-related social restrictions and analyse the relationships between those factors. Design: A qualitative descriptive design was used to collect... Read More about Identifying how pre-existing resources combine to shape the experiences of work and family life of a diverse sample of working parents with at least one child in primary school in Scotland during COVID-19 pandemic-related social restrictions: a qualitative descriptive design.

Effects of catchment land use on temperate mangrove forests (2024)
Journal Article
Thomson, T., Ellis, J. I., Fusi, M., Prinz, N., Lundquist, C. J., Bury, S. J., Shankar, U., Cary, S. C., & Pilditch, C. A. (2024). Effects of catchment land use on temperate mangrove forests. Science of the Total Environment, 940, Article 173579. https://doi.org/10.1016/j.scitotenv.2024.173579

Human land use changes are threatening the integrity and health of coastal ecosystems worldwide. Intensified land use for anthropogenic purposes increases sedimentation rates, pollutants, and nutrient concentrations into adjacent coastal areas, often... Read More about Effects of catchment land use on temperate mangrove forests.