Genetic variability of Chlamydophila abortus strains assessed by PCR-RFLP analysis of polymorphic membrane protein-encoding genes

Saita, Michelle; Clarka, Ewan M; Wheelhouse, Nicholas; Spalding, Lucy; Livingstone, Morag; Sachse, Konrad; Markey, Bryan K; Magnino, Simone; Siarkou, Victoria I; Vretou, Evangelia; Caro, Mar�a R; Yaga, Raja; Lainson, F Alex; Smith, David G E; Wright, Frank; Longbottom, David

doi:10.1016/j.vetmic.2011.03.005

All Outputs (7)

New challenges for vaccination to prevent chlamydial abortion in sheep (2011)
Journal Article
Entrican, G., Wheelhouse, N., Wattegedera, S. R., & Longbottom, D. (2012). New challenges for vaccination to prevent chlamydial abortion in sheep. Comparative Immunology, Microbiology and Infectious Diseases, 35(3), 271-276. https://doi.org/10.1016/j.cimid.2011.12.001

Ovine enzootic abortion (OEA) is caused by the obligate intracellular Gram-negative bacterium Chlamydia abortus. OEA remains a common cause of infectious abortion in many sheep-rearing countries despite the existence of commercially available vaccine... Read More about New challenges for vaccination to prevent chlamydial abortion in sheep.

Endemic and emerging chlamydial infections of animals and their zoonotic implications (2011)
Journal Article
Wheelhouse, N., & Longbottom, D. (2011). Endemic and emerging chlamydial infections of animals and their zoonotic implications. Transboundary and Emerging Diseases, 59(4), 283-291. https://doi.org/10.1111/j.1865-1682.2011.01274.x

The Chlamydiae are a diverse group of obligate intracellular Gram-negative bacteria that are known to infect a wide variety of host species and are responsible for a wide range of diseases in animals and man. Many of these organisms have been extensi... Read More about Endemic and emerging chlamydial infections of animals and their zoonotic implications.

Identification, sequencing and molecular analysis of Chp4, a novel chlamydiaphage of Chlamydophila abortus belonging to the family Microviridae (2011)
Journal Article
Sait, M., Livingstone, M., Graham, R., Inglis, N. F., Wheelhouse, N., & Longbottom, D. (2011). Identification, sequencing and molecular analysis of Chp4, a novel chlamydiaphage of Chlamydophila abortus belonging to the family Microviridae. Journal of General Virology, 92(7), 1733-1737. https://doi.org/10.1099/vir.0.031583-0

Members of the family Microviridae have been identified in a number of chlamydial species infecting humans (phage CPAR39 in Chlamydophila pneumoniae), other mammals (phiCPG1 in Chlamydophila caviae, Chp2 in Chlamydophila abortus and Chp3 in Chlamydop... Read More about Identification, sequencing and molecular analysis of Chp4, a novel chlamydiaphage of Chlamydophila abortus belonging to the family Microviridae.

Genome sequence of the Chlamydophila abortus variant strain LLG (2011)
Journal Article
Sait, M., Clark, E. M., Wheelhouse, N., Livingstone, M., Spalding, L., Siarkou, V. I., …Longbottom, D. (2011). Genome sequence of the Chlamydophila abortus variant strain LLG. Journal of Bacteriology, 193(16), 4276-4277. https://doi.org/10.1128/JB.05290-11

Chlamydophila abortus is a common cause of ruminant abortion. Here we report the genome sequence of strain LLG, which differs genotypically and phenotypically from the wild-type strain S26/3. Genome sequencing revealed differences between LLG and S26... Read More about Genome sequence of the Chlamydophila abortus variant strain LLG.

Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks (2011)
Journal Article
Lowrie, A. G., Dickinson, P., Wheelhouse, N., Stewart, G. D., Ross, A. J., Forster, T., & Ross, J. A. (2011). Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks. International Journal of Oncology, 39(3), 709-18. https://doi.org/10.3892/ijo.2011.1064

Dermcidin is a candidate oncogene capable of increasing the number of cultured neuronal, breast cancer and prostate cancer cells and improving the survival of hepatic cells. The dermcidin gene encodes the proteolysis-inducing factor core pepti... Read More about Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks.

Molecular detection of Chlamydia-like organisms in cattle drinking water (2011)
Journal Article
Wheelhouse, N., Saita, M., Gidlow, J., Deuchande, R., Borel, N., Baily, J., Caldow, G., & Longbottom, D. (2011). Molecular detection of Chlamydia-like organisms in cattle drinking water. Veterinary Microbiology, 152(1-2), 196-199. https://doi.org/10.1016/j.vetmic.2011.03.040

A substantial proportion of the causes of infectious bovine abortion remain largely undiagnosed, potentially due to the presence of previously unrecognised infectious agents. Recently, several reports have demonstrated the presence of Parachlamydia s... Read More about Molecular detection of Chlamydia-like organisms in cattle drinking water.

Genetic variability of Chlamydophila abortus strains assessed by PCR-RFLP analysis of polymorphic membrane protein-encoding genes (2011)
Journal Article
Saita, M., Clarka, E. M., Wheelhouse, N., Spalding, L., Livingstone, M., Sachse, K., Markey, B. K., Magnino, S., Siarkou, V. I., Vretou, E., Caro, M. R., Yaga, R., Lainson, F. A., Smith, D. G. E., Wright, F., & Longbottom, D. (2011). Genetic variability of Chlamydophila abortus strains assessed by PCR-RFLP analysis of polymorphic membrane protein-encoding genes. Veterinary Microbiology, 151(3-4), 284-290. https://doi.org/10.1016/j.vetmic.2011.03.005

This study used PCR-RFLP to investigate the genetic variability of pmp-encoding genes from fifty-two Chlamydophila abortus (C. abortus) strains originating from abortion cases from various geographical regions and host species. Six primer pairs were... Read More about Genetic variability of Chlamydophila abortus strains assessed by PCR-RFLP analysis of polymorphic membrane protein-encoding genes.