All Outputs (2)

Development of mitochondria- and protease-specific prodrugs in the potential treatment of parasitic helminth infections (2016)
Presentation / Conference Contribution
Oluwadare, E., Rehan, A., Ding, Y., Turnbull, A., Malone, E., Mincher, D., & Proudfoot, L. (2016, September). Development of mitochondria- and protease-specific prodrugs in the potential treatment of parasitic helminth infections. Poster presented at Mol

Anthelmintic resistance and the shortage of new drugs represent an urgent need for the development of novel anti-parasite drugs with effective delivery to the target site. Reduced bioavailability and sub-optimal doses can be responsible for generatio... Read More about Development of mitochondria- and protease-specific prodrugs in the potential treatment of parasitic helminth infections.

Cationic host defense peptides; novel antimicrobial therapeutics against Category A pathogens and emerging infections (2016)
Journal Article
Findlay, F., Proudfoot, L., Stevens, C., & Barlow, P. G. (2016). Cationic host defense peptides; novel antimicrobial therapeutics against Category A pathogens and emerging infections. Pathogens and Global Health, 110(4-5), 137-147. https://doi.org/10.1080/20477724.2016.1195036

Cationic Host Defense Peptides (HDP, also known as antimicrobial peptides) are crucial components of the innate immune system and possess broad-spectrum antibacterial, antiviral, and immunomodulatory activities. They can contribute to the rapid clear... Read More about Cationic host defense peptides; novel antimicrobial therapeutics against Category A pathogens and emerging infections.