Rep provides a second motor at the replisome to promote duplication of protein-bound DNA
(2009)
Journal Article
Guy, C., Atkinson, J., Gupta, M., Mahdi, A., Gwynn, E., Rudolph, C., Moon, P., van Knippenberg, I., Cadman, C., Dillingham, M., Lloyd, R., & McGlynn, P. (2009). Rep provides a second motor at the replisome to promote duplication of protein-bound DNA. Molecular Cell, 36(4), 654-666. https://doi.org/10.1016/j.molcel.2009.11.009
Nucleoprotein complexes present challenges to genome stability by acting as potent blocks to replication. One attractive model of how such conflicts are resolved is direct targeting of blocked forks by helicases with the ability to displace the block... Read More about Rep provides a second motor at the replisome to promote duplication of protein-bound DNA.