Indexes of polar interactions between ionizable drugs and membrane phospholipids measured by IAM–HPLC: Their relationships with data of Blood–Brain Barrier passage
(2014)
Journal Article
Grumetto, L., Russo, G., & Barbato, F. (2014). Indexes of polar interactions between ionizable drugs and membrane phospholipids measured by IAM–HPLC: Their relationships with data of Blood–Brain Barrier passage. European Journal of Pharmaceutical Scie
Phospholipid affinity indexes (log k IAM/w) for 21 structurally non-related basic, acidic, ampholytic, and neutral drugs were measured by HPLC on two different phospholipid stationary phases (Immobilized Artificial Membrane – IAM). The differences b... Read More about Indexes of polar interactions between ionizable drugs and membrane phospholipids measured by IAM–HPLC: Their relationships with data of Blood–Brain Barrier passage.