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All Outputs (5)

P1‐034: A role for lithium in rescuing amyloid beta pathology in an inducible drosophila model of Alzheimer's disease (2015)
Presentation / Conference Contribution
Adesakin, O. A., Kerr, F., & Partridge, L. (2015, July). P1‐034: A role for lithium in rescuing amyloid beta pathology in an inducible drosophila model of Alzheimer's disease. Presented at Alzheimer's Association International Conference, Washington, D.C., USA

Background
Alzheimer's disease (AD) is the leading cause of dementia in the ageing population. Amyloid beta (Ab) accumulation, which occurs as a result of the amyloidogenic processing of amyloid precursor protein (APP), is thought to initiate the pa... Read More about P1‐034: A role for lithium in rescuing amyloid beta pathology in an inducible drosophila model of Alzheimer's disease.

P1‐274: Ageing increases vulnerability to Aβ42 toxicity in drosophila (2012)
Presentation / Conference Contribution
Kerr, F., Rogers, I., Martinez, P., Hardy, J., Lovestone, S., & Partridge, L. (2012, July). P1‐274: Ageing increases vulnerability to Aβ42 toxicity in drosophila. Presented at Alzheimer 's Association International Conference 2012, Vancouver, British Columbia

Background
Ageing is the major risk factor for the development of many neurodegenerative diseases, including Alzheimer's Disease (AD). One of the major unresolved questions in the AD field asks why neurodegeneration occurs late in life. This associa... Read More about P1‐274: Ageing increases vulnerability to Aβ42 toxicity in drosophila.

P1‐066: Dietary restriction delays ageing, but not neuronal pathology, in drosophila models of Alzheimer's disease (2008)
Presentation / Conference Contribution
Kerr, F., Partridge, L., & AddNeuroMed consortium. (2008, July). P1‐066: Dietary restriction delays ageing, but not neuronal pathology, in drosophila models of Alzheimer's disease. Presented at Alzheimer's Association International Conference on Alzheimer's Disease, Chicago, Illinois

Background
Dietary restriction (DR) extends lifespan in diverse organisms and can delay a range of ageing-related diseases including Alzheimer's disease (AD), whereas high-fat diets are suggested to be an important environmental risk factor for AD.... Read More about P1‐066: Dietary restriction delays ageing, but not neuronal pathology, in drosophila models of Alzheimer's disease.