All Outputs (6)

Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep (2011)
Journal Article
Dolan, S., Gunn, M. D., Crossan, C., & Nolan, A. M. (2011). Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep. Behavioural Pharmacology, 22, 582-588. https://doi.org/10.1097/FBP.0b013e3283478802

This study set out to characterize the contribution of group III metabotropic glutamate receptor 7 activation to nociceptive behaviour and mechanical hypersensitivity in a novel formalin test in sheep. The mGlu receptor 7 allosteric agonist, N,N′-dib... Read More about Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep.

Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia (2011)
Journal Article
Dolan, S., Hastie, P. G. R., Crossan, C., & Nolan, A. M. (2011). Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia. Molecular Pain, 7, 91. https://doi.org/10.1186/1744-8069-7-91

Background This study characterised the effects of persistent peripheral inflammation of the foot on pain and spinal cord expression of cyclooxygenase-1 and -2 (COX-1 and COX-2) and early growth response gene 1 (Egr-1), known markers of neuronal p... Read More about Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia.

Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1) (2011)
Journal Article
Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. M. (2011). Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1). Animal Welfare, 20(4), 535=548

Health-related quality of life (HRQL) was defined for farmed animals and identified as an appropriate focus of integrative welfare measurement for farmed pigs that embraces measurement of positive welfare. The instrument for HRQL measurement was de... Read More about Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1).

Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2) (2011)
Journal Article
Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. (2011). Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2). Animal Welfare, 20(4), 549-558

The development of a novel structured questionnaire instrument to measure health-related quality of life (HRQL) in individual farmed pigs was described previously (companion paper). The instrument embraces the measurement of positive welfare, and was... Read More about Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2).

Quality of life is reduced in obese dogs but improves after successful weight loss (2011)
Journal Article
German, A. J., Holden, S. L., Wiseman-Orr, M. L., Reid, J., Nolan, A. M., Biourge, V., …Scott, E. M. (2012). Quality of life is reduced in obese dogs but improves after successful weight loss. Veterinary Journal, 192(3), 428-434. https://doi.org/10.1016/j.tvjl.2011.09.015

Obesity is thought to affect quality of life, but limited objective data exist to support this supposition. The current study aim was to use a questionnaire to determine health-related quality of life (HRQOL) both before and after weight loss, in obe... Read More about Quality of life is reduced in obese dogs but improves after successful weight loss.

The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs (2011)
Journal Article
Sandercock, D. A., Gibson, I. F., Rutherford, K. M. D., Donald, R. D., Lawrence, A. B., Brash, H. M., …Nolan, A. M. (2011). The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs. Physiology and Behavior, 104(5), 728-737. https://doi.org/10.1016/j.physbeh.2011.07.018

The consequences of tail-docking (at 2–4 days) and prenatal stress (maternal social stress during the 2nd third of pregnancy) on baseline nociceptive thresholds and responses to acute inflammatory challenge were investigated in juvenile pigs in two s... Read More about The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs.