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An international multi-site, randomized controlled trial of a mindfulness-based psychoeducation group programme for people with schizophrenia

Chien, W. T.; Bressington, D.; Yip, A.; Karatzias, T.

Authors

W. T. Chien

D. Bressington



Abstract

Background
We aimed to test a mindfulness-based psycho-education group (MBPEG), versus conventional psycho-education group (CPEG) versus treatment-as-usual (TAU), in patients with schizophrenia-spectrum disorders over a 24-month follow-up.
Methods
This single-blind, multi-site, pragmatic randomized controlled trial was conducted in six community treatment facilities across three countries (Hong Kong, mainland China and Taiwan). Patients were randomly allocated to one of the treatment conditions, and underwent six months of treatment. The primary outcomes were changes in duration of rehospitalizations and mental state (PANSS) between baseline and one week, six, 12 and 18 months’ post treatment.
Results
A total of 300 patients in each country were assessed for eligibility between October 2013 and 30 April 2014,38 patients per country (n=342) were assigned to each treatment group and included in the intention-to-treat-analysis. There was a significant difference in the length of re-hospitalizations between the three groups over 24 months F (2,330) =5.23, p=0.005, with MBPEG participants having a shorter mean duration of re-hospitalizations than those in the
other groups. The MBPEG and CPEG participants had significant differential changes in proportional ORs of complete remission (all individual PANSS items

Citation

Chien, W. T., Bressington, D., Yip, A., & Karatzias, T. (2017). An international multi-site, randomized controlled trial of a mindfulness-based psychoeducation group programme for people with schizophrenia. Psychological Medicine, 47(12), 2081-2096. https://doi.org/10.1017/s0033291717000526

Journal Article Type Article
Acceptance Date Feb 7, 2017
Online Publication Date Apr 4, 2017
Publication Date 2017-09
Deposit Date Feb 13, 2017
Publicly Available Date Mar 29, 2024
Journal Psychological Medicine
Print ISSN 0033-2917
Electronic ISSN 1469-8978
Publisher Cambridge University Press
Peer Reviewed Peer Reviewed
Volume 47
Issue 12
Pages 2081-2096
DOI https://doi.org/10.1017/s0033291717000526
Keywords Applied Psychology; Psychiatry and Mental health
Public URL http://researchrepository.napier.ac.uk/Output/684417

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Copyright Statement
© Cambridge University Press 2017
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.






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