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How important is reprocessing in personalized multicomponent therapy? Analyzing longitudinal data of inpatients with severe PTSD

Kratzer, Leonhard; Heinz, Peter; Knefel, Matthias; Weindl, Dina; Tschöke, Stefan; Biedermann, Sarah V.; Schröder, Johanna; Karatzias, Thanos


Leonhard Kratzer

Peter Heinz

Matthias Knefel

Dina Weindl

Stefan Tschöke

Sarah V. Biedermann

Johanna Schröder


Treatment guidelines for complex presentations of posttraumatic stress disorder (PTSD) are often cautious about the reprocessing of traumatic memories and recommend multicomponent treatments that are widely used in clinical practice. Yet, the role of reprocessing in these multicomponent treatments remains unknown. Using naturalistic data of 97 patients treated for PTSD, we used a linear mixed model to investigate the role of reprocessing for the outcome at discharge and at 6-month follow-up. Treatment effects were significant and large (g = 0.91–1.05). The final model showed good fit and explained 51% of the variance. There was a significant main effect of time (B = −8.1 [−11.5; −4.8], p < 0.001), as well as a reprocessing by time interaction (B = −17.2 [−30.5; −3.8], p = 0.012), indicating better outcomes with higher levels of reprocessing. Hence, maximizing the amount of reprocessing used in multicomponent treatments for PTSD may significantly enhance outcomes.

Journal Article Type Article
Acceptance Date Mar 15, 2023
Online Publication Date May 11, 2023
Publication Date 2023-08
Deposit Date Mar 17, 2023
Publicly Available Date May 12, 2024
Print ISSN 0022-3018
Electronic ISSN 1539-736X
Publisher Lippincott, Williams & Wilkins
Peer Reviewed Peer Reviewed
Volume 211
Issue 8
Pages 592-600
Keywords Posttraumatic Stress Disorder, Eye Movement Desensitization and Reprocessing (EMDR), Exposure


How Important Is Reprocessing In Personalized Multicomponent Therapy? Analyzing Longitudinal Data Of Inpatients With Severe PTSD (accepted version) (1 Mb)

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