Dr Giacomo Russo G.Russo@napier.ac.uk
Lecturer
Development and Validation of a LC-FD Method for the Simultaneous Determination of Eight Bisphenols in Soft Drinks
Russo, Giacomo; Barbato, Francesco; Grumetto, Lucia
Authors
Francesco Barbato
Lucia Grumetto
Abstract
Bisphenol A (BPA) is a chemical widely used as a monomer in the production of polymers of plastics. It acts as an endocrine-disrupting agent and thus its contaminations of food and beverage should be carefully monitored in order to assess consumers’ risk. In this study, we propose a liquid chromatography-fluorescence detection (LC-FD)-validated method for the simultaneous determination of BPA and seven analogues, i.e., bisphenol AF, bisphenol B, bisphenol E, bisphenol F, BPA diglycidyl ether, bisphenol F diglycidyl ether, and Bisphenol M in soft drinks. A one-step solid-phase extraction (SPE) was effective at reducing the interferences, obtaining good purification of the samples, and consequently good recoveries of all analytes. The separation was obtained on a C18 column by using acetonitrile/water 55:45 (v/v) under isocratic conditions. Method validation was performed according to the European Commission Decision 2002/657/EC criteria, providing good results regarding the analytical parameters of linearity, selectivity, sensitivity, precision, recovery, decision limit (CCα), detection capability (CCβ), limit of detection (LOD), limit of quantification (LOQ), stability, and robustness. The method allows the detection of BPA and BADGE at levels much lower than their legal limits in the food, which are 0.06 and 9.00 mg kg−1, respectively.
Citation
Russo, G., Barbato, F., & Grumetto, L. (2016). Development and Validation of a LC-FD Method for the Simultaneous Determination of Eight Bisphenols in Soft Drinks. Food Analytical Methods, 9(10), 2732-2740. https://doi.org/10.1007/s12161-016-0458-x
| Journal Article Type | Article |
|---|---|
| Acceptance Date | Feb 22, 2016 |
| Online Publication Date | Mar 3, 2016 |
| Publication Date | 2016-10 |
| Deposit Date | May 4, 2020 |
| Journal | Food Analytical Methods |
| Print ISSN | 1936-9751 |
| Electronic ISSN | 1936-976X |
| Publisher | BMC |
| Peer Reviewed | Peer Reviewed |
| Volume | 9 |
| Issue | 10 |
| Pages | 2732-2740 |
| DOI | https://doi.org/10.1007/s12161-016-0458-x |
| Keywords | Food Science; Analytical Chemistry; Applied Microbiology and Biotechnology; Safety Research; Safety, Risk, Reliability and Quality |
| Public URL | http://researchrepository.napier.ac.uk/Output/2658251 |