Guidelines for the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA).

Brown, Derek F J; Edwards, David I; Hawkey, Peter M; Morrison, Donald; Ridgway, Geoffrey L; Towner, Kevin J; Wren, Michael W D

Abstract

These evidence-based guidelines have been produced after a literature review of the laboratory diagnosis
and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA). We have considered
the detection of MRSA in screening samples and the detection of reduced susceptibility to glycopeptides
in S. aureus. Recommendations are given for the identification of S. aureus and for suitable methods
of susceptibility testing and screening for MRSA and for S. aureus with reduced susceptibility to glycopeptides.
These guidelines indicate what tests should be used but not when the tests are applicable,
as aspects of this are dealt with in guidelines on control ofMRSA.There are currently several developments
in screening media and molecular methods. It is likely that some of our recommendations will require
modification as the new methods become available.

Citation

Brown, D. F. J., Edwards, D. I., Hawkey, P. M., Morrison, D., Ridgway, G. L., Towner, K. J., & Wren, M. W. D. (2005). Guidelines for the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA). Journal of Antimicrobial Chemotherapy, 56, 1000-1018. https://doi.org/10.1093/jac/dki372

• Journal Article Type: Article
• Publication Date: 2005
• Deposit Date: Jun 12, 2015
• Print ISSN: 0305-7453
• Electronic ISSN: 1460-2091
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 56
• Pages: 1000-1018
• DOI: https://doi.org/10.1093/jac/dki372
• Keywords: MRSA identification; MRSA susceptibility testing; MRSA screening; MRSA molecular methods; GISA; ; methicillin
• Public URL: http://researchrepository.napier.ac.uk/id/eprint/8685
• Publisher URL: http://dx.doi.org/10.1093/jac/dki372