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Applications of Deep Learning and Reinforcement Learning to Biological Data

Mahmud, Mufti; Kaiser, Mohammed Shamim; Hussain, Amir; Vassanelli, Stefano


Mufti Mahmud

Mohammed Shamim Kaiser

Stefano Vassanelli


Rapid advances in hardware-based technologies during the past decades have opened up new possibilities for life scientists to gather multimodal data in various application domains, such as omics, bioimaging, medical imaging, and (brain/body)-machine interfaces. These have generated novel opportunities for development of dedicated data-intensive machine learning techniques. In particular, recent research in deep learning (DL), reinforcement learning (RL), and their combination (deep RL) promise to revolutionize the future of artificial intelligence. The growth in computational power accompanied by faster and increased data storage, and declining computing costs have already allowed scientists in various fields to apply these techniques on data sets that were previously intractable owing to their size and complexity. This paper provides a comprehensive survey on the application of DL, RL, and deep RL techniques in mining biological data. In addition, we compare the performances of DL techniques when applied to different data sets across various application domains. Finally, we outline open issues in this challenging research area and discuss future development perspectives.

Journal Article Type Article
Online Publication Date Jan 31, 2018
Publication Date 2018-06
Deposit Date Jul 19, 2019
Journal IEEE Transactions on Neural Networks and Learning Systems
Print ISSN 2162-237X
Electronic ISSN 2162-2388
Publisher Institute of Electrical and Electronics Engineers
Peer Reviewed Peer Reviewed
Volume 29
Issue 6
Pages 2063-2079
Keywords Bioimaging, brain–machine interfaces, convolutional neural network (CNN), deep autoencoder (DA), deep belief network (DBN), deep learning performance, medical imaging, omics, recurrent neural network (RNN)
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