Immobilized Artificial Membrane HPLC Derived Parameters vs PAMPA-BBB Data in Estimating in Situ Measured Blood–Brain Barrier Permeation of Drugs
(2016)
Journal Article
Grumetto, L., Russo, G., & Barbato, F. (2016). Immobilized Artificial Membrane HPLC Derived Parameters vs PAMPA-BBB Data in Estimating in Situ Measured Blood–Brain Barrier Permeation of Drugs. Molecular Pharmaceutics, 13(8), 2808-2816. https://doi.org/10.1021/acs.molpharmaceut.6b00397
The affinity indexes for phospholipids (log kWIAM) for 42 compounds were measured by high performance liquid chromatography (HPLC) on two different phospholipid-based stationary phases (immobilized artificial membrane, IAM), i.e., IAM.PC.MG and IAM.P... Read More about Immobilized Artificial Membrane HPLC Derived Parameters vs PAMPA-BBB Data in Estimating in Situ Measured Blood–Brain Barrier Permeation of Drugs.