The intermediate filament protein, vimentin, is a regulator of NOD2 activity
(2012)
Journal Article
Stevens, C., Henderson, P., Nimmo, E. R., Soares, D. C., Dogan, B., Simpson, K. W., Barrett, J. C., Wilson, D. C., & Satsangi, J. (2013). The intermediate filament protein, vimentin, is a regulator of NOD2 activity. Gut, 62(5), 695-707. https://doi.org/10.1136/gutjnl-2011-301775
Objective Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Having previously identified vimentin as a novel NOD2-interacting protein, the a... Read More about The intermediate filament protein, vimentin, is a regulator of NOD2 activity.