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Chk2 activates E2F-1 in response to DNA damage (2003)
Journal Article
Stevens, C., Smith, L., & La Thangue, N. B. (2003). Chk2 activates E2F-1 in response to DNA damage. Nature Cell Biology, 5(5), 401-409. https://doi.org/10.1038/ncb974

The E2F-1 transcription factor is regulated during cell cycle progression and induced by cellular stress, such as DNA damage. We report that checkpoint kinase 2 (Chk2) regulates E2F-1 activity in response to the DNA-damaging agent etoposide. A Chk2 c... Read More about Chk2 activates E2F-1 in response to DNA damage.

Changes in sediment processes across the western Irish Sea front. (2003)
Journal Article
Gowen, R., Stewart, B., & Trimmer, M. (2003). Changes in sediment processes across the western Irish Sea front. Estuarine, Coastal and Shelf Science, 56(5-6), 1011-1019. https://doi.org/10.1016/S0272-7714%2802%2900312-8

Sediment characteristics, sediment respiration (oxygen uptake and sulphate reduction) and sediment–water nutrient exchange, in conjunction with water column structure and phytoplankton biomass were measured at five stations across the western Irish S... Read More about Changes in sediment processes across the western Irish Sea front..

Stereospecific synthesis of chiral caprolactone monomers from D-glucose. (2003)
Journal Article
Defossemont, G., & Mincher, D. (2003). Stereospecific synthesis of chiral caprolactone monomers from D-glucose. Carbohydrate Research, 338(6), 563-565. https://doi.org/10.1016/S0008-6215%2802%2900490-1

The synthesis and characterisation of a novel chiral bicyclic oxacaprolactone is reported. The choice of diisopropylidene- -glucose as a starting material allowed selective introduction of the synthetic equivalent necessary for the formation of the s... Read More about Stereospecific synthesis of chiral caprolactone monomers from D-glucose..

E2F and cell cycle control: a double-edged sword (2003)
Journal Article
Stevens, C., & La Thangue, N. B. (2003). E2F and cell cycle control: a double-edged sword. Archives of Biochemistry and Biophysics, 412(2), 157-169. https://doi.org/10.1016/s0003-9861%2803%2900054-7

The E2F family of transcription factors plays a central role in regulating cellular proliferation by controlling the expression of both the genes required for cell cycle progression, particularly DNA synthesis, and the genes involved with apoptosis.... Read More about E2F and cell cycle control: a double-edged sword.

Indicator taxa for the conservation of pond invertebrate diversity (2003)
Journal Article
Briers, R. A., & Biggs, J. (2003). Indicator taxa for the conservation of pond invertebrate diversity. Aquatic Conservation: Marine and Freshwater Ecosystems, 13(4), 323-330. https://doi.org/10.1002/aqc.576

1.Ponds are a valuable resource for the conservation of freshwater biodiversity, but are often extremely numerous in a given area, making assessment of the conservation value of individual sites potentially time consuming.* 2.The use of indicator tax... Read More about Indicator taxa for the conservation of pond invertebrate diversity.

Flight activity of adult stoneflies in relation to weather (2003)
Journal Article
Briers, R. A., Cariss, H. M., & Gee, J. H. R. (2003). Flight activity of adult stoneflies in relation to weather. Ecological Entomology, 28(1), 31-40. https://doi.org/10.1046/j.1365-2311.2003.00480.x

1. Dispersal of adult aquatic insects between streams may have important consequences for local and regional population dynamics, but little is known about how dispersal is affected by weather conditions.2. The influence of meteorological variables o... Read More about Flight activity of adult stoneflies in relation to weather.

Can postlarval bivalves select sediment type during settlement? A field test with Macoma balthica (L.) and Cerastoderma edule (L.) (2003)
Journal Article
Huxham, M., & Richards, M. (2003). Can postlarval bivalves select sediment type during settlement? A field test with Macoma balthica (L.) and Cerastoderma edule (L.). Journal of Experimental Marine Biology and Ecology, 288(2), 279-293. https://doi.org/10.1016/s0022-0981%2803%2900023-6

Many soft-bottom benthic invertebrates display sediment-associated patterns of dispersion. Habitat selection experiments have shown that the larvae of some species can choose to settle in favourable habitats, and this process could establish patterns... Read More about Can postlarval bivalves select sediment type during settlement? A field test with Macoma balthica (L.) and Cerastoderma edule (L.).

Depletion of Drad21/Scc1 in Drosophila Cells Leads to Instability of the Cohesin Complex and Disruption of Mitotic Progression (2003)
Journal Article
Vass, S., Cotterill, S., Valdeolmillos, A. M., Barbero, J. L., Lin, E., Warren, W. D., & Heck, M. M. (2003). Depletion of Drad21/Scc1 in Drosophila Cells Leads to Instability of the Cohesin Complex and Disruption of Mitotic Progression. Current Biology, 13(3), 208-218. https://doi.org/10.1016/S0960-9822%2803%2900047-2

Background: The coordination of cell cycle events is necessary to ensure the proper duplication and dissemination of the genome. In this study, we examine the consequences of depleting Drad21 and SA, two non-SMC subunits of the cohesin complex, by ds... Read More about Depletion of Drad21/Scc1 in Drosophila Cells Leads to Instability of the Cohesin Complex and Disruption of Mitotic Progression.

Range size and environmental calcium requirements of British freshwater gastropods (2003)
Journal Article
Briers, R. A. (2003). Range size and environmental calcium requirements of British freshwater gastropods. Global Ecology and Biogeography, 12(1), 47-51. https://doi.org/10.1046/j.1466-822X.2003.00316.x

Calcium is an essential requirement for the successful growth and development of gastropod molluscs. Data for British freshwater gastropods were used to examine the relationship between environmental calcium requirements and British and European rang... Read More about Range size and environmental calcium requirements of British freshwater gastropods.

Gingivitis and Toothbrushes: potential roles in Viridans Streptococcal Bacteraemia. (2003)
Journal Article
Kennedy, H. F., Morrison, D., Tomlinson, D., Gibson, B. E., Bagg, J., & Gemmell, C. G. (2003). Gingivitis and Toothbrushes: potential roles in Viridans Streptococcal Bacteraemia. Journal of Infection, 46(1), 67-70. https://doi.org/10.1053/jinf.2002.1084

We report a case of Streptococcus oralis bacteraemia in a paediatric neutropenic patient with acute myeloid leukaemia whose predominant form of oral compromise was severe gingivitis, rather than mucositis. By phenotypic and genotypic analyses, the st... Read More about Gingivitis and Toothbrushes: potential roles in Viridans Streptococcal Bacteraemia..