Outputs (2)

Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life (2019)
Presentation / Conference Contribution
Siemienowicz, K., Filis, P., Shaw, S., Douglas, A., Thomas, J., Howie, F., Fowler, P., Duncan, C., & Rae, M. (2019, May). Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life. Presented at 21st European Congress of Endocrinology, Lyon, France

Introduction: Adult male offspring of women with PCOS have increased dyslipidaemia, characterised by elevated triglycerides (TG), increased total and LDL-cholesterol (LDL-C), and hyperinsulinaemia. As altered intrauterine endocrine environments can ‘... Read More about Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life.

Fetal androgen exposure is a determinant of adult male metabolic health (2019)
Journal Article
Siemienowicz, K. J., Filis, P., Shaw, S., Douglas, A., Thomas, J., Mulroy, S., Howie, F., Fowler, P. A., Duncan, W. C., & Rae, M. T. (2019). Fetal androgen exposure is a determinant of adult male metabolic health. Scientific Reports, 9, Article 20195 (2019). https://doi.org/10.1038/s41598-019-56790-4

Androgen signalling is a critical driver of male development. Fetal steroid signalling can be dysregulated by a range of environmental insults and clinical conditions. We hypothesised that poor adult male health was partially attributable to aberrant... Read More about Fetal androgen exposure is a determinant of adult male metabolic health.