Prof Nick Wheelhouse's Outputs (2)

The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle (2007)
Journal Article
Qiu, G.-H., Salto-Tellez, M., Ross, J. A., Yeo, W., Cui, Y., Wheelhouse, N., Chen, G. G., Harrison, D., Lai, P., Tao, Q., & Hooi, S. C. (2008). The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle. Journal of Hepatology, 48(3), 433-441. https://doi.org/10.1016/j.jhep.2007.11.015

Background/Aims: The chromosome locus 3p21.3 is a ‘‘hot-spot” for chromosomal aberrations and loss of heterozygosity in cancers. The 35 genes mapped to the AP20 subregion of this locus were screened for their expression to identify candidate tumor su... Read More about The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle.

Effect of high-fat enteral nutrition on hepatocyte injury in response to hemorrhagic shock in the rat (2007)
Journal Article
Chu, M. M., Luyer, M. D. P., Wheelhouse, N. M., Bellamy, C. O., Greve, J. W. M., Buurman, W. A., Sangster, K., Fearon, K. C. H., Ross, J. A., Garden, O. J., Dejong, C. H. C., & Wigmore, S. J. (2007). Effect of high-fat enteral nutrition on hepatocyte injury in response to hemorrhagic shock in the rat. World Journal of Surgery, 31(8), 1693-1701. https://doi.org/10.1007/s00268-007-9107-2

BACKGROUND: High-fat enteral nutrition reduces the inflammatory response following hemorrhagic shock in the rat. AIMS: We hypothesized that this intervention might also ameliorate the remote organ injury to the liver associated with this model. METHO... Read More about Effect of high-fat enteral nutrition on hepatocyte injury in response to hemorrhagic shock in the rat.