Keratins regulate β‐cell mitochondrial morphology, motility, and homeostasis
(2017)
Journal Article
Silvander, J. S. G., Kvarnström, S. M., Kumari‐Ilieva, A., Shrestha, A., Alam, C. M., & Toivola, D. M. (2017). Keratins regulate β‐cell mitochondrial morphology, motility, and homeostasis. FASEB Journal, 31(10), 4578-4587. https://doi.org/10.1096/fj.201700095r
Loss of the epithelial intermediate filament protein keratin 8 (K8) in murine β cells leads to irregular insulin vesicles and decreased insulin levels. Because mitochondria are central in glucose-stimulated insulin secretion, the relationship between... Read More about Keratins regulate β‐cell mitochondrial morphology, motility, and homeostasis.