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BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1.

Oughtred, Rose; Chatr-aryamontri, Andrew; Breitkreutz, Bobby-Joe; Chang, Christie S.; Rust, Jennifer M.; Theesfeld, Chandra L.; Heinicke, Sven; Breitkreutz, Ashton; Chen, Daici; Hirschman, Jodi; Kolas, Nadine; Livstone, Michael S.; Nixon, Julie; O�Donnell, Lara; Ramage, Lindsay; Winter, Andrew; Reguly, Teresa; Sellam, Adnane; Stark, Chris; Boucher, Lorrie; Dolinski, Kara; Tyers, Mike

Authors

Rose Oughtred

Andrew Chatr-aryamontri

Bobby-Joe Breitkreutz

Christie S. Chang

Jennifer M. Rust

Chandra L. Theesfeld

Sven Heinicke

Ashton Breitkreutz

Daici Chen

Jodi Hirschman

Nadine Kolas

Michael S. Livstone

Julie Nixon

Lara O�Donnell

Lindsay Ramage

Andrew Winter

Teresa Reguly

Adnane Sellam

Chris Stark

Lorrie Boucher

Kara Dolinski

Mike Tyers



Abstract

The Biological General Repository for Interaction Datasets (BioGRID) is a freely available public database that provides the biological and biomedical research communities with curated protein and genetic interaction data. Structured experimental evidence codes, an intuitive search interface, and visualization tools enable the discovery of individual gene, protein, or biological network function. BioGRID houses interaction data for the major model organism species—including yeast, nematode, fly, zebrafish, mouse, and human—with particular emphasis on the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe as pioneer eukaryotic models for network biology. BioGRID has achieved comprehensive curation coverage of the entire literature for these two major yeast models, which is actively maintained through monthly curation updates. As of September 2015, BioGRID houses approximately 335,400 biological interactions for budding yeast and approximately 67,800 interactions for fission yeast. BioGRID also supports an integrated posttranslational modification (PTM) viewer that incorporates more than 20,100 yeast phosphorylation sites curated through its sister database, the PhosphoGRID.

Citation

Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B., Chang, C. S., Rust, J. M., Theesfeld, C. L., Heinicke, S., Breitkreutz, A., Chen, D., Hirschman, J., Kolas, N., Livstone, M. S., Nixon, J., O’Donnell, L., Ramage, L., Winter, A., Reguly, T., Sellam, A., Stark, C., Boucher, L., …Tyers, M. (2016). BioGRID: A Resource for Studying Biological Interactions in Yeast: Table 1. Cold Spring Harbor protocols, 2016(1), pdb.top080754. https://doi.org/10.1101/pdb.top080754

Journal Article Type Article
Acceptance Date Dec 1, 2015
Online Publication Date Jan 4, 2016
Publication Date 2016-01
Deposit Date Mar 25, 2017
Journal Cold Spring Harbor Protocols
Print ISSN 1940-3402
Electronic ISSN 1559-6095
Peer Reviewed Peer Reviewed
Volume 2016
Issue 1
Pages pdb.top080754
DOI https://doi.org/10.1101/pdb.top080754
Keywords Biochemistry, Genetics and Molecular Biology(all)
Public URL http://researchrepository.napier.ac.uk/Output/819967




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