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New developments in osteoarthritis and cartilage biology

Poulet, Blandine; Staines, Katherine A


Blandine Poulet

Katherine A Staines


Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Characterised by articular cartilage loss, subchondral bone thickening and osteophyte formation, the OA joint afflicts much pain and disability. Whilst OA has been associated with many contributing factors, its underpinning molecular mechanisms are, nevertheless, not fully understood. Clinical management of OA is largely palliative and there is an ever growing need for an effective disease modifying treatment. This review discusses some of the recent progress in OA therapies in the different joint tissues affected by OA pathology.


Poulet, B., & Staines, K. A. (2016). New developments in osteoarthritis and cartilage biology. Current Opinion in Pharmacology, 28, 8-13.

Journal Article Type Article
Online Publication Date Feb 26, 2016
Publication Date 2016-06
Deposit Date Jan 13, 2017
Publicly Available Date Nov 22, 2019
Journal Current Opinion in Pharmacology
Print ISSN 1471-4892
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 28
Pages 8-13
Keywords Pharmacology; Drug Discovery
Public URL


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