Mindfulness-based interventions for non-affective psychosis: A comprehensive systematic review and meta-analysis

Lai King Yip, Annie; Karatzias, Thanos; Tong Chien, Wai

Abstract

Aim: Although mindfulness-based interventions (MBIs) are routinely used in clinical practice, a comprehensive synthesis of the effectiveness of MBIs for non-affective psychosis has yet to be conducted. The aim in the present review and meta-analysis was to investigate the effectiveness of MBIs including those with mindfulness as an active treatment component at alleviating symptoms of psychosis to inform future clinical practice.
Methods: A systematic review of studies published in journals or in dissertations in CINAHL, PubMed, EMBASE, PsycINFO, CENTRAL, ISRCTN or CNKI from January 1990 until December 2020. A total of 31 eligible studies (n=2,146) were included.
Results: Effect-size estimates suggested that 22 independent samples (n=1,632) produced a statistically significant small effect for psychotic symptoms (g=-0.48), and with a clinically significant reduction of 50% from baseline (pooled OR: 1.84). Separate meta-analyses demonstrated small effects for affective symptoms (g=-0.44) and small-to-large positive effects for quality of life (g=0.38), mindfulness skills (g=0.45), and insight into illness/treatment (g=1.35). The heterogeneity was high across the studies.
Conclusion: Results suggest that short-term MBIs can be beneficial for non-affective psychosis. Future research is needed to test the efficacy and safety of dedicated MBIs for this population group over a longer-term.

Citation

Lai King Yip, A., Karatzias, T., & Tong Chien, W. (2022). Mindfulness-based interventions for non-affective psychosis: A comprehensive systematic review and meta-analysis. Annals of Medicine, 54(1), 2340-2353. https://doi.org/10.1080/07853890.2022.2108551

• Journal Article Type: Article
• Acceptance Date: Jul 29, 2022
• Online Publication Date: Aug 25, 2022
• Publication Date: 2022
• Deposit Date: Aug 5, 2022
• Publicly Available Date: Aug 25, 2022
• Journal: Annals of Medicine
• Print ISSN: 0785-3890
• Electronic ISSN: 1365-2060
• Publisher: Taylor & Francis
• Peer Reviewed: Peer Reviewed
• Volume: 54
• Issue: 1
• Pages: 2340-2353
• DOI: https://doi.org/10.1080/07853890.2022.2108551
• Public URL: http://researchrepository.napier.ac.uk/Output/2894681