Are deprivation-specific cancer survival patterns similar according to individual- and area-based measures? A cohort study of patients diagnosed with five malignancies in England & Wales, 2008-2016

Woods, Laura M.; Belot, Aur�lien; Atherton, Iain; Ellis-Brookes, Lucy; Baker, Mat; Ingleby, Fiona C.

Abstract

Objective: To investigate if measured inequalities in cancer survival differ when using individual- (‘person’) compared to area- (‘place’) based measures of deprivation for three socio-economic dimensions: income, deprivation and occupation
Design: Cohort study
Setting: Data from the Office for National Statistics (ONS) Longitudinal Study of England and Wales, UK, linked to the National Cancer Registration Database
Participants: Patients diagnosed with cancers of the colorectum, breast, prostate, bladder or with Non-Hodgkin Lymphoma (NHL) during the period 2008-2016
Primary and secondary outcome measures: Differentials in net survival between groups defined by individual wage, occupation and education compared to those obtained from corresponding area-level metrics using the English and Welsh Indices of Multiple Deprivation (IMD).
Results: Survival was negatively associated with area-based deprivation irrespective of the type analysed, although a trend from least to most deprived was not always observed. Socio-economic differences were present according to individually-measured socio-economic groups although there was an absence of a consistent ‘gradient’ in survival. The magnitude of differentials was similar for area-based and individually-derived measures of deprivation, which was unexpected.
Conclusion: These unique data suggest that the socio-economic influence of ‘person’ is different to that of ‘place’ with respect to cancer outcomes. This has implications for health policy aimed at reducing inequalities. Further research could further consider the separate and additional influence of area-based deprivation over individual-level characteristics (contextual effects) as well as investigate the geographic, socio-economic and healthcare related characteristics of areas with poor outcomes in order to inform policy intervention.

Citation

Woods, L. M., Belot, A., Atherton, I., Ellis-Brookes, L., Baker, M., & Ingleby, F. C. (2022). Are deprivation-specific cancer survival patterns similar according to individual- and area-based measures? A cohort study of patients diagnosed with five malignancies in England & Wales, 2008-2016. BMJ Open, 12(6), Article e058411. https://doi.org/10.1136/bmjopen-2021-058411

• Journal Article Type: Article
• Acceptance Date: May 13, 2022
• Online Publication Date: Jun 10, 2022
• Publication Date: 2022-06
• Deposit Date: Jun 8, 2022
• Publicly Available Date: Jun 10, 2022
• Journal: BMJ Open
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 12
• Issue: 6
• Article Number: e058411
• DOI: https://doi.org/10.1136/bmjopen-2021-058411
• Public URL: http://researchrepository.napier.ac.uk/Output/2877181